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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Rapid detection of minimal residual disease in acute myeloid leukemia from peripheral blood

    SBC: BIOFLUIDICA, INC.            Topic: 102

    AbstractAcute myeloid leukemiaAMLis the most common adult leukemia withnew cases expected inin the US and ayear survival rate of onlyThe primary cause of death for AML is due to disease relapseThe consequences of relapse are significant with it not atypical to see a relapse rate ofof which onlysurvive afteryearsIf clinicians could easily identify a patient s minimum residual diseaseMRDbefore the t ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. Development of a mobile and automated platform for multiplexed multi-modality imaging

    SBC: Sonovol, Inc.            Topic: 102

    Abstract Bioluminescence imagingBLIsystems are installed in thousands of facilities and labsand with their straightforward and low cost workflow for longitudinal studiesare the most commonly used preclinical modality for assessing tumor models in rodentsThere currently is no high throughput and low cost system enabling BLI images to be combined with anatomical images of soft tissue to confirm tumo ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. HLS-Highly-Sensitive, One-minute, Portable Diagnostic for Malaria Elimination

    SBC: Hemex Health, Inc.            Topic: NIAID

    Project SummaryWhile the mosquito borne illness malariais entirely preventable and treatablecountries are currently plagued by malaria transmission and half the world s population is at risk of malariaA great deal of progress has been made against malaria as a result of the massive rollout of resources and technology focused on malaria controlThirty five of theaffected countriesincluding China and ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Novel Fiber Scaffolding for Effective Removal of Diverse Hazardous Chemicals from Water

    SBC: Chemica Technologies, Inc            Topic: 113

    DESCRIPTIONprovided by applicantThe water treatment product developed in this SBIR program will give more people the opportunity to live healthier lives and strengthen communities by increasing available water resourcesThe contamination of drinking water is an age old problemIn recent decadesthe pollution of ground and drinking water by organic chemicals has attracted increasing attention all over ...

    SBIR Phase II 2017 Department of Health and Human Services
  5. Development of an oral therapeutic to mimic the anti-diabetic effects of gastric bypass surgery

    SBC: BIOKIER, INC.            Topic: 200

    DESCRIPTIONprovided by applicantGlucose homeostasis and regulation of food intake are both promoted by the secretion of gut hormones following nutrient stimulation of enteroendocrine cellsL cellsin the lower gutThis process is impaired in diabetes but is restored when delivery of dietary compounds such as amino acids and fatty acids to the lower gut is facilitatedThis effect of delivery of nutrien ...

    SBIR Phase II 2017 Department of Health and Human Services
  6. HOME: Monitoring Balance and Gait with the Home Objective Mobility Exam

    SBC: APDM, INC.            Topic: NIA

    Project Summary Frailty is a common clinical condition in which older adults are at high risk for fallsdisabilityhospitalizationand deathApproximatelyof adultsyears or older are frail andare prefrail with high risk of progressing to frailtyCurrent screening for frailty hinges on infrequent o ce visits and a patient s report of symptomswhich often fail to detect subtle declineImpaired physical func ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. Development of an H2O2-inactivated chikungunya virus vaccine

    SBC: NAJIT TECHNOLOGIES, INC.            Topic: R

    Chikungunya virusCHIKVis an alphavirus that has gained significant attention due to its ability to cause large epidemics among susceptible populations and to be spread beyond endemic countries by international travelersAmong a population of approximatelyon the French island of La Reunionpeople were infected and overCHIKV related fatalities occurred during theoutbreakLikewisean estimatedmillion peo ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Automated Isolation of Single Cells Using High-Resolution and Subcellular Imaging

    SBC: Cell Microsystems, Inc.            Topic: 400

    PROJECT SUMMARYPairingdetailedphenotypiccharacterizationofcellswithdownstreammolecularanalysisrepresentsasignificant challengeespecially at the level of single cellsCell Microsystems has developed and commercializedthe CellRaftSystemwhich is currently the only commercially available means of imaging cells using brightfieldand or multichannel fluorescence prior to single cell isolation and downstre ...

    SBIR Phase II 2017 Department of Health and Human Services
  9. Parent-Teen Communication to Resist Unhealthy Media Messages

    SBC: Innovation Research And Training, Inc.            Topic: NICHD

    ABSTRACT The disturbingly high rates of early and risky sexual behaviors of adolescents and the glamorization of risky sexual behavior in the media suggest the need for new evidence basedcomprehensive sex education programs for adolescentsParents serve as a major socialization agent for their teens and they can help improve adolescentsoutcomes by increasing their communication with their children ...

    SBIR Phase II 2017 Department of Health and Human Services
  10. Web Software to develop an RDoC Compatible Adaptive Diagnostic Nosology the SID

    SBC: Health Outcomes Inc            Topic: 102

    n psychiatry clinical judgment has been the predominant method of diagnosis The `gold standard for clinical research is the Structured Clinical Interview for DSM SCID The SCID promotes reliability but its validity is questionable There is growing recognition that biomarkers can be used to identify more homogeneous patient populations but there is substantial phenotypic discordance f ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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