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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Rapid detection of minimal residual disease in acute myeloid leukemia from peripheral blood

    SBC: BIOFLUIDICA, INC.            Topic: 102

    AbstractAcute myeloid leukemiaAMLis the most common adult leukemia withnew cases expected inin the US and ayear survival rate of onlyThe primary cause of death for AML is due to disease relapseThe consequences of relapse are significant with it not atypical to see a relapse rate ofof which onlysurvive afteryearsIf clinicians could easily identify a patient s minimum residual diseaseMRDbefore the t ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. Analytical Methods for Automated Quality Control of Cancer PET Imaging Tracer- [F-18]FDG

    SBC: Trace-Ability, Inc.            Topic: 102

    Project SummaryPositron Emission TomographyPETis regarded as a standard of care in the management of multiple types of cancerAvailability of this procedure relies on a steady supply of a radioactive contrast agentFFluorodeoxy d glucoseFDGDue to the inherent short half lifeminmultiple batches of FDG are typically produced at multiple sites on daily basisQuality ControlQCof FDG remains the most labo ...

    SBIR Phase II 2017 Department of Health and Human Services
  3. Web Application for Methodologically Rigorous Animal Study Design

    SBC: STOCHASTECH CORPORATION            Topic: NIDA

    PROJECT SUMMARY ABSTRACTOur goal in this SBIR effort is to produce a web based suite of tools and services to help researchers design methodologically sound experiments for improved research outcomes and reproducibility of resultsDesignAssist provides a promising approach that connects animal researchers to experimental design expertisedelivering a cost effective solutionalleviating the need for i ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Development of a mobile and automated platform for multiplexed multi-modality imaging

    SBC: Sonovol, Inc.            Topic: 102

    Abstract Bioluminescence imagingBLIsystems are installed in thousands of facilities and labsand with their straightforward and low cost workflow for longitudinal studiesare the most commonly used preclinical modality for assessing tumor models in rodentsThere currently is no high throughput and low cost system enabling BLI images to be combined with anatomical images of soft tissue to confirm tumo ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. HLS-Highly-Sensitive, One-minute, Portable Diagnostic for Malaria Elimination

    SBC: Hemex Health, Inc.            Topic: NIAID

    Project SummaryWhile the mosquito borne illness malariais entirely preventable and treatablecountries are currently plagued by malaria transmission and half the world s population is at risk of malariaA great deal of progress has been made against malaria as a result of the massive rollout of resources and technology focused on malaria controlThirty five of theaffected countriesincluding China and ...

    SBIR Phase II 2017 Department of Health and Human Services
  6. Primity Cloud: High-Performance Cytometry Analysis Engine

    SBC: PRIMITY BIO, INC.            Topic: NIAID

    Project SummaryFlow cytometry is an indispensable tool for interrogating the immune system in researchdrug discovery and diagnostic applicationsThe platform has undergone tremendous expansion over the past decade and nowmodern cytometers are able to analyzetoparameters per single cellfor millions of cells per sampleand hundreds of samples per experimentHoweveras the number of parameterssamplesand ...

    SBIR Phase II 2017 Department of Health and Human Services
  7. A New Filter Paper Technology for Flavivirus Collection, Shipping, and Analysis

    SBC: GenTegra LLC            Topic: NIAID

    Abstract The Flavivirusesespecially DengueZika and Yellow Fever have been a major public health concern for centuries in semi and tropical climatesincluding parts of the southern USPresentlythese viruses are the cause of more thanmillion infections per yearGlobal travelalteration of the underlying mosquito vector s geographical rangethe possibility of RNA genome mutation resulting from vector chan ...

    SBIR Phase II 2017 Department of Health and Human Services
  8. Low-Cost Instrument-free Point-of-Care Diagnostic for Neisseria gonorrhoeae

    SBC: Lucira Health, Inc.            Topic: NIAID

    Abstract Neisseria gonorrhoeaeGCis the second most common cause of bacterial sexually transmitted diseasesSTDwith an estimated world prevalence ofmillionApproximatelycases occur annually in the U Sbut over half are unreportedand rates continue to rise as indicated by aincrease fromtoGC is a major cause of pelvic inflammatory diseasePIDthat can lead to tubal factor infertilityectopic pregnancy and ...

    SBIR Phase II 2017 Department of Health and Human Services
  9. Development of a versatile robotic radiation therapy system

    SBC: Radiabeam Technologies, LLC            Topic: 102

    SignificanceRobotic radiotherapy using extensively non coplanar beams has been shown effective to significantly improve radiation therapy dosimetryleading to improved treatment outcomesHoweverthe current implementation of this technique by CyberKnife is inefficient and not dosimetrically optimalThis has severely limited both the number of patients eligible for robotic radiotherapy and the achievab ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Cell Line Panel Profiling for Discovery of Multiple Myeloma Therapeutics

    SBC: PRIMITY BIO, INC.            Topic: 102

    Project Summary Drug combination therapy has revolutionized cancer treatment and is now the mainstay of most modern regimensIn spite of the successit is evident that in most casesthe cancer either does not respond to the initial treatment or a form of the cancer emerges that is cross resistant to multiple drugsInvestigation into the molecular causes of cancer and dramatic improvements to the drug ...

    SBIR Phase II 2017 Department of Health and Human Services
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