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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Structure-based discovery of dopamine D1 receptor selective small molecule ligands

    SBC: CONFOMETRX, INC.            Topic: 101

    Dopamine receptors are a family of G protein-coupled receptors (GPCRs), and can be further divided into D1-like (D1 and D5) and D2-like (D2, D3 and D4) subfamilies. In this proposal, we focus on D1 receptor, which is widely expressed in brain at high levels. Modulation of D1 activity is implicated in the treatment of many psychiatric and neurological disorders, such as schizophrenia, attention def ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Rapid and Simple Paper Strip Test for the Multiplexed Detection of Gastrointestinal Pathogens at the Point-of-Need

    SBC: Godx Inc.            Topic: 950

    PROJECT SUMMARY GoDx, Inc. has been developing a prototype multiplexed paper strip device for the detection of the DNA and RNA of gastrointestinal pathogens at the point-of-need in andlt; 30 minutes with funding from the NCATS SBIR parent grant TR 001912. We have used the same platform technology we are developing in the parent grant to develop a rapid (andlt;30 minute), low-cost and instrument-fr ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a Functional Balloon-borne GNSS-RO System Prototype

    SBC: Night Crew Labs, LLC            Topic: 811

    The SBIR Phase II proposal outlines the approach of Night Crew Labs (NCL) in designing, and developing, and testing a system prototype to perform Global Navigation Satellite System radio occultations (GNSS-ROs) from a high-altitude balloon platform. NCL will continue building from the positive results achieved in Phase I that successfully demonstrated the feasibility of performing balloon-borne GN ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  4. Sea Tag-SP: A family of acoustic enabled satellite tags for spawning detection and more

    SBC: DESERT STAR SYSTEMS, LLC            Topic: 812

    Phase-1 demonstrated the powerful and unusual remote sensing opportunities available by adding acoustic signal detection to pop-up satellite tags (PSAT). The time and location of spawning define the starting point in the life history of fish. Yet this event, which is of critical importance to fishery researchers and managers seeking to gain an understanding of distinct reproductive populations and ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  5. Low-cost Mooring Location Beacon for Coastal Applications

    SBC: TOYON RESEARCH CORPORATION            Topic: 825

    Subsurface mooring beacons are used to provide notifications and assist in locating moored assets that have surfaced and are free drifting. Their nominal design is driven by the requirements for offshore use where they need to survive extreme depths and remote deployment, most often using satellite constellations for communication and geo-location. Existing beacons serve their purpose well, but th ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  6. Fog Viewer

    SBC: Arete Associates            Topic: 826

    The presence of fog reduces visibility, contributing to unsafe conditions for many maritime tasks. The current system uses active backscatter and has high power requirements, high maintenance and replacement costs. Areté Associates’ innovative FogViewer system comprises a passive multi-spectral, multi-polarization sensor suite that leverages available degrees of freedom to best characterize the ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  7. Bottom Feeder- A Highly Maneuverable Autonomous Underwater Vehicle

    SBC: Tridentis Advanced Marine Vehicles LLC            Topic: 822

    The Bottom Feeder project is designed to prove out the research done in Phase I using a prototype platform. The prototype will be a full size version of the platform designed during Phase I. The Phase I platform was designed to work in two operational configurations, a highly efficient mode and a highly maneuverable mode, with the ability to switch between them while submerged. The platform is equ ...

    SBIR Phase II 2019 Department of CommerceNational Oceanic and Atmospheric Administration
  8. Rapid Point-of-Care Diagnostics to Detect Serologic Status of Individuals for Select Viral Infections

    SBC: ZYMERON CORP            Topic: NIAID

    CytomegalovirusCMVis a very common intrauterine infectionaffecting approximately one in everychildrenThe overall disease burden in the US with congenital CMV was estimated at $billion annuallyCMV is also a cause of serious morbidity and fatal infections in immunocompromised patientsThere is currently no generally accepted therapy and developing a CMV vaccine is high priorityCurrently CMV trials re ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Rapid diagnostic to determine CMV serological status

    SBC: NANOCOMPOSIX, INC.            Topic: NIAID

    The goal of this project is to develop a diagnostic that can support the enrollment of seronegative individuals in clinical trials of candidate cytomegalovirusCMVvaccinesCongenital CMV infection is one of the leading causes of non genetic birth defects worldwideIf a successful vaccine can be brought to marketit will have a significant impact on the number of babies born with hearing and vision los ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. TOPIC 359: A DEVICE PROTOTYPE FOR ISOLATION OF MELANOMA EXOSOMES FOR DIAGNOSTICS AND TREATMENT MONITORING

    SBC: Aethlon Medical, Inc.            Topic: NCI

    The proposed work aims to develop a pre commercial prototype of an exosome isolation device to be used in clinical diagnostic laboratoriesWe will advance the device to facilitate exosome isolation for downstream liquid biopsy tests requiring analysis of proteinDNAor microRNAwhich rely upon acquisition of intact and pure exosomesThe device strategy will be designed to isolate total exosomes and the ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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