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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Co-culture cassette for anaerobes and primary human intestinal epithelium

    SBC: Altis Biosystems, Inc.            Topic: 300

    Project SummaryThe human colon is a remarkable organ, playing critical roles in drug uptake and metabolism as well as harboring the 100 trillion microbial cells of the microbiome, which itself has multiple impacts on human health. For these reasons, there is a widespread need in academia and the biotechnology marketplace for in vitro studies of human colon physiology and the interaction between co ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. User-driven Retrospectively Supervised Classification Updating (RESCU) system for robust upper limb prosthesis control

    SBC: INFINITE BIOMEDICAL TECHNOLOGIES, LLC            Topic: 105

    TBD

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School

    SBC: OREGON RESEARCH BEHAVIORAL INTERVENTION STRATEGIES, INC.            Topic: 400

    Abstract Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations often arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e., “deviant peer clustering”). Even though the field has developed efficacious school-based prevention programs, program effects are generally small, and t ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Increased sensitivity of minimal residual disease monitoring using peripheral blood in pediatric patients with acute lymphoblastic leukemia

    SBC: BIOFLUIDICA, INC.            Topic: 102

    Abstract Acute lymphoblastic leukemia (ALL) is the most common malignant disease in childhood and accounts for approximately 30% of all cancers diagnosed before the age of 18 years (1). The primary cause of death for ALL patients is disease relapse. Therefore, monitoring for minimal residual disease (MRD) is considered the most powerful predictor of outcome in acute leukemias, including B-type acu ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. ALow Blood Volume Platform for Global Newborn Screening of Common, Treatable Conditions

    SBC: BAEBIES, INC.            Topic: NICHD

    An estimated 80% of babies born worldwide (approximately 100 million each year) currently do not receive any newborn screening care. Newborn screening (NBS) is an immensely successful testing program that identifies those at increased risk for common, treatable congenital disorders; the pre-symptomatic identification of these disorders in newborns enables the rapid initiation of treatments and red ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Low Cost Image Guidance for Improved Vessel Cannulation in Pediatric Patients

    SBC: CLEAR GUIDE MEDICAL, INC.            Topic: NICHD

    The use of ultrasound for placement of many IVs in pediatric cases has significantly enhanced the success of Central Vein Catheterizations (andquot;CVCsandquot;), although ultrasound can often be hard for non- specialists to use. Although ultrasound guidance can certainly facilitate vascular access, it takes practice and experience to master the real-time ultrasound, free hand technique. The value ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Long Acting rhTSH Superagonist Analogs for Improved Diagnostic Imaging, Thyroglobulin Stimulation and Therapy of Thyroid Cancer.

    SBC: TROPHOGEN INC            Topic: 102

    Thyroid cancer is the most common malignancy of endocrine tissues, disproportionally affecting women, and is one of the few cancers greatly increasing in incidence andamp; prevalence for unknown reasons. A very aggressive form of this cancer may result from nuclear accidents like Chernobyl andamp; Fukushima, increasing proximity of nuclear waste storage sites, or from nuclear explosions including ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Selection and preclinical development of a bacteria-targeting, non-antibiotic lead candidate to improve cancer chemotherapy outcomes

    SBC: SYMBERIX, INC.            Topic: 102

    The long-term objective of this project is a therapeutic adjunct to prevent chemotherapy-induced diarrhea (CID) based on a completely new mechanism of action targeting enteric bacteria. This Fast-Track SBIR proposal outlines the strategy for selecting a lead development candidate to be evaluated in investigational new drug (IND)-enabling studies to support a first-in-human trial. The focus of this ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Development and Validation of a Collaborative Web/Cloud-Based Dosimetry System for Radiopharmaceutical Therapy.

    SBC: RADIOPHARMACEUTICAL IMAGING AND DOSIMETRY, LLC            Topic: 101

    Project SummaryRadiopharmaceutical therapy (RPT) – the use of targeted radionuclides to deliver radiation specifically to cancer cells and their microenvironment – is a fundamentally different approach to cancer therapy that is growing, with a substantial number of large and small pharmaceuticals companies developing products in this area and radionuclide producers making substantial investmen ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Multiplex Platform for Point-of-Care Newborn Screening of Hyperbilirubinemia

    SBC: BAEBIES, INC.            Topic: NICHD

    ABSTRACT Multiplex Platform for Point-of-Care Newborn Screening of Hyperbilirubinemia (SBIR Phase IIB) Hyperbilirubinemia (jaundice) affects more than half of all newborns and is typically benign if identified and treated promptly. Without proper treatment, high bilirubin leads to serious neurological dysfunction including neuro-motor, auditory, speech, cognition, and language disturbances. Rapid ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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