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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nanoliter Lab-on-a-chip for Protein Crystallization

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): The human genome contains at least 30,000 unique open reading frames that may yield >100,000 polypeptide products. These products assemble into more than a million biologically relevant structures or proteins of interest per organism. Crystallization and X-ray diffraction of these proteins is routinely performed to determine their 3D structure which needs to be ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Nanoliter Lab-on-a-Chip for Blood Diagnostics

    SBC: ADVANCED LIQUID LOGIC            Topic: N/A

    DESCRIPTION (provided by applicant): Latrogenic blood loss or "bleeding into the laboratory" is an important reason for administration of small volume transfusions in very low birth weight premature 6infants. A direct correlation was found between the volume of blood drawn for diagnostics and subsequent volume transfused. In neonatal infants, there may not be enough collected blood sample to perfo ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Improved Orthopedic Implant Surface Coatings

    SBC: AFFINERGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Many contemporary medical and dental therapies include the replacement or repair of tissues using materials such as metal. Currently there are at least 150,000 hip replacements, 300,000 knee replacements, and 500,000 dental implant procedures performed in the US each year (Kurtz, Mowat et al. 2005). These numbers are expected to increase as the baby boom gen ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Development Of A Pulsed Light Emitting Diode Dental Photocuring System

    SBC: B & W TEK INC            Topic: N/A

    DESCRIPTION (provided by applicant): LED based curing lights are beginning to replace conventional halogen lamps as the first choice for dental photo-curing applications. The target of this proposal is to develop a new generation LED dental curing light. It will be the first curing light that is optimized according to the kinetic response of the dental composite, which plays a key role in determin ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Clinical Development a Therapeutic Agent for COPD

    SBC: BIOMARCK PHARMACEUTICALS, LTD            Topic: N/A

    Hypersecretion of mucus into the respiratory airways is a major contributing factor in several lung diseases, including chronic pulmonary disease (COPD), asthma, cystic fibrosis, and bronchiectasis. Despite the obvious medical importance, there presently are no effective therapies to control excess mucus secretion in these diseases, and very few potential therapeutic targets. We discovered that a ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Ophthalmic Optical Coherence Tomography

    SBC: BIOPTIGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II Small Business Innovative Research application proposes to dramatically expand the commercial availability of optical coherence tomography (OCT) technology for pre-clinical human and animal research applications by commercializing Fourier-domain OCT (FD-OCT) technology and developing robust interfaces for retinal OCT imaging in a wide variety of s ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Home Sensor Date Fusion to Support Aging in Place

    SBC: CLEVERSET, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The aging of the U.S. population presents many challenges. The existing paradigm of care will not allocate resources efficiently as the size of the population requiring home care assistance grows. Our objective is to enhance elder independence by providing both better and more timely predictive health-status assessments and direct, real-time, recommendations an ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  8. IDENTIFICATION OF NEW ACETYL-COA CARBOXYLASE INHIBITORS

    SBC: CROPSOLUTION, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Acetyl-CoA carboxylase (ACC) catalyzes the first step in fatty acid biosynthesis and its product, malonyl-CoA, inhibits fatty acid oxidation. These functions make ACC a prime target for the development of therapeutics to treat obesity and type 2 diabetes. Knockout studies in mice, and animal studies with ACC inhibitors, have validated this approach. The most po ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Tobacco World: Interactive Tobacco Education for Teens

    SBC: DESCHUTES RESEARCH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed project will develop an interactive computer-based program for tobacco prevention aimed at middle school students. The CD-ROM is designed to be an adjunct to the existing health education curriculum provided for 6th through 8th grades. The CD-ROM is based upon our Phase I prototype program entitled Tobacco World in which students are presented wit ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  10. VLSI for Ambulatory EEG Epilepsy Monitoring

    SBC: Electrical Geodesics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): This research will create a small and inexpensive multichannel physiological data acquisition system. It will allow dense array (128 or 256 channel) EEG systems to be made at a similar cost as conventional (19 or 32 channels) systems, and it will allow conventional systems to become very compact and inexpensive. The initial implementation will be an ambulatory ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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