Award Data

Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

In this effort, NuSpot Technologies, LLC proposes the development of a cost-effective, self-contained and easy to manufacture Superresolving Phase Filter capable of generating a sub-wavelength scale, or “superresolved,” spot of electromagnetic radiation that can be customized to operate at a given target wavelength in the IR, Vis, or UV. Successful completion of this SBIR project will enable: ...

Over a decade ago, security practitioners highlighted threats posed by memory corruption exploits subverting systems through manipulation of security-critical non-control-data — without ever corrupting application control-flow. Since that demonstration, however, the full power of data-oriented attacks went largely unnoticed until very recently. One reason for this recent emergence is that exploi ...

BioMojo proposes to develop a language-based intelligent patient simulation platform for the purpose of providing students with a realistic training environment and instructors better control over the training environment involving simulated patients.

Current balance and gait assessment practices in field environments lack adequate sensitivity to measure subtle but potentially duty-limiting deficits in Service Member (SM) performance. Clinicians endeavor to provide timely, evidence-based assessment of

The Phase I and Phase II projects that are the basis for this Phase II enhancement proposal tested the feasibility of releasing opiate compounds from a topical wound dressing for burn pain relief and treatment. This project culminated with a regulatory s

This Phase II Small Business Innovation Research project develops the scale of lithium-ion direct recycling technologies applied to gain efficiencies in materials management from original manufacturing to end-of-life. The scrap materials are from Defense Logistics Agency manufacturing activities. A successful effort moves direct recycle TRL from 4 to 6, increases process throughput, qualifies mate ...

To satisfy the need for a radiation-hardened, 1064-nm laser sensitive, single-photon sensitive ladar camera, with pixel counts of 128 x 128 or more, a proven single-photon linear-mode InGaAs(P)/InAlAs avalanche-photodiode (APD) detector will be integrated with low-noise ladar readout integrated circuits (ROICs), and its performance will be shown compatible with missile defense mission requirements ...

Vadum has demonstrated the Optimal Advanced Hypervelocity Projectile (HVP) Trajectory System (OATHS) which increases the performance of the HVP by optimizing HVP trajectory to its target. OATHS was prototyped and tested using an in-house MATLAB-based combat system development environment. The results of Phase I testing show that OATHS can feasibly increase HVP probability of kill or reduce the tot ...

Traditional active 3D imaging systems, such as airborne and terrestrial lidar scanners, use a transmitter and receiver typically co-located on the same platform and connected in synchronous communications. However, recent advances in laser, detector, and airborne systems technology have opened the door to smaller, higher-performance and significantly lower-cost airborne lidar systems in which it i ...