Award Data

This project addresses the need for increased opportunities for customized employment for individuals with cognitive disabilities by developing the Person-Centered Planning ToolKit. The Toolkit will enhance implementation of personcentered planning (PCP), often limited by lack of follow-through on action items and a lack of tools to match career preferences to specific customized employment opport ...

This project develops and tests a Bluetooth compliant tongue-based electronic controller (a.k.a. “Mouth Mouse”), designed to give people with upper limb disability control of peripheral devices including computers and communication systems, home automation, and powered wheelchairs, as well as many other Bluetooth compliant devices and new technologies to come in the future. The Mouth Mouse is ...

This project creates an online, interactive, self-paced mindfulness intervention program specifically designed for adolescents with chromosome 22q11.2 deletion syndrome (22q11DS), a common genetic disorder. The goal of the project is to adapt and examine the usability of a novel online mindfulness training program for adolescents (ages 13 to 18) with 22q11DS. To date, there are very few behavioral ...

This project develops and evaluates an intelligent web-based application, Tools for Reading to Acquire Content Knowledge (TRACK) for middle and high school students with neurocognitive deficits such as individuals with learning disabilities, attention deficit/hyperactivity disorder, traumatic brain injury, or autism spectrum disorder. Applying a participatory action research approach, investigator ...

Development of Novel PDE B Inhibitors to Treat Alcohol Use Disorder

TuberculosisTBkilled an estimatedmillion people in the world inOverof the mortalities associated with this deisease occurred in regions of the world where access to reliable TB testing and other suppotive infrastructure is severely limitedUntil there are pivotal technological innovations in the diagnosis of TB for point of carePOCapplicationthe ambitious goals of the WHO s End TB strategyareductio ...

The recombinant HIV SOSIP EnvelopeEnvtrimer is the leading HIV vaccine candidate but current production levels are low in mammalian cell lineslikely due to current trimer designs which include numerous disulfide bondsproteolytic cleavage and extensive glycosylationknown to induce endoplasmic reticulumERstress and cellular toxicityThis proposal will utilize the Nicotiana benthamiana pN bpplant expr ...

Nucleic acid testing offers the potential to improve tuberculosis diagnosis world wideHigh purity DNA is essential to the success of virtually any downstream nucleic acid detection methodWe propose to develop a sample preparation system to extract and purify Mycobacterium tuberculosis DNA from raw sputumThe project goalas described in the solicitationPHSTopicis to develop an inexpensive and easy t ...

This research project seeks to create innovative software that aids healthcare providers to calculate the out of pocket costs of patients receiving cancer treatmentThe goals of this SBIR project are to leverage the insights of stakeholderssubject matter experts and industry standards to create a software system that can be integrated into the workflow of providersIf we are successfulhealthcare pro ...

The goal of this SBIR project is to create a prototype of an innovative software system to help cancer survivors better manage their symptoms and stay connected with their clinicians over the course of their livesThis will include enabling survivors to report symptoms they may be experiencingcollect and transmit real time measurements from wearable sensors and receive notifications and reminders t ...