Award Data

Nerve agents exert their toxic effect by binding to and inactivating enzyme acetylcholinesterase, a key enzymatic regulator of cholinergic neurotransmission. The binding becomes irreversible after a varying amount of time with nerve agents and this aging process limits the treatment window of oxime reactivators. To enhance the current antidote treatment of nerve agent autoinjectors, a pyridostigmi ...

The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

This proposal presents a Phase I SBIR project to develop a high precision, low disperse rate powder disseminator for the US Army. In the development of the sensitive detecting agent, we need to release a precise amount of C&B agents in the controlled detection experiments. However, such a technology does not exist at the present time. After examining existing technologies, we believe that the r ...