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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High-throughput functional analysis and clinical relevance of all possible variants of a gene

    SBC: HELIGENICS, INC.            Topic: NHGRI

    Modern pharmaceuticals have greatly improved the quality of life for many patients suffering a variety of illnesses. Unfortunately, among the 17 most commonly prescribed drugs, only 6 are highly effective for most patients, 5 have a modest effect, and 6 show little clinical effect. Worse still, unwanted illness and death from treatment of patients with the incorrect drug or dosage causes over 275, ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. A micronized electrostatic precipitator for next-generation respiratory protection against pathogenic aerosols

    SBC: HENLEY ION, LLC            Topic: NIAID

    PROJECT SUMMARY Many pathogens, such as severe acute respiratory coronavirus 2 (SARS-CoV-2) and Mycobacterium tuberculosis, spread via aerosol transmission and inflict global public health and economic consequences. SARS-CoV-2 has infected over 450 million people, led to over 6 million fatalities, and caused major economic losses. The tuberculosis-causing bacterium and longstanding global health e ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Point-of-care lateral flow immunoassay for diagnosis of pertussis

    SBC: DXDISCOVERY INC            Topic: NIAID

    Pertussis (Whooping cough) is a highly contagious, airborne disease that is rapidly re-emerging as a serious public health threat in the United States. Despite high vaccine coverage, annual reported cases in the U.S. have been increasing recently, with an average of 25,000 per year from 2010-2019. This is a level unseen since the early 1960s. Diagnosis of pertussis is challenging because its early ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy

    SBC: STRYKAGEN CORPORATION            Topic: 100

    Abstract Duchenne Muscular Dystrophy (DMD) is a fatal muscle disease with an incidence of 1 in 5000 males. DMD results from mutations in the gene encoding dystrophin, a 427 kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and laminin in the extracellular matrix. The α7β1 integrin is a transmembrane linkage system in skeletal and card ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Novel non-narcotic analgesic for acute and chronic pain

    SBC: South Rampart Pharma, LLC            Topic: 106

    PROJECT SUMMARYSouth Rampart Pharma (SRP) is an early clinical-stage company focused on developing SRP-001, a novel non-opioid designed to treat moderate-to-severe acute and chronic pain without the dose-limiting hepatotoxicity of acetaminophen and nephrotoxicity of NSAIDs, and the misuse and addictive potential of opioids. SRP-001 is currently in Phase 1 trials where interim data support the expe ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Advancing next-generation sequencing for optimization of rAAV production

    SBC: BIOINFOEXPERTS LLC            Topic: FDA

    1 BioInfoExperts develops pathogen-associated next-generation sequencing (NGS) analytics and software for a2 growing number of industries that require genome characterization. In the proposed SBIR Phase I project, we3 will develop NGS analytics for the recombinant adeno-associated viruses (rAAVs) manufacturing industry; in4 Phase II, we will incorporate the NGS analytics into a a software-as-a-ser ...

    SBIR Phase I 2023 Department of Health and Human ServicesFood and Drug Administration
  7. Healthy Cooking Basics.

    SBC: LEARNING Q LLC            Topic: NIDILRR

    This project develops and tests HEALTHY COOKING BASICS, a microlearning curriculum for people with intellectual and developmental disabilities (IDD) to be used with the LearningQ platform currently in development. The curriculum is used as a tool within Independent Living programs, Health and Wellness, and Workforce Training, and provides 25-30 new skills organized into badges. The HEALTHY COOKING ...

    SBIR Phase I 2023 Department of Health and Human ServicesAdministration for Community Living
  8. Workforce Basics

    SBC: LEARNING Q LLC            Topic: NIDILRR

    The project develops and tests WORKFORCE BASICS, a microlearning curriculum for people with intellectual and developmental disabilities (IDD) for the LearningQ platform currently in development. The goal of the project is to improve access to and effectiveness of workforce training by augmenting existing programs with on-demand microlearning resources and tools. WORKFORCE BASICS is an extended wor ...

    SBIR Phase I 2023 Department of Health and Human ServicesAdministration for Community Living
  9. The Atalanta—Artificial Muscle Powered Above-Knee Prosthesis to Significantly Improve Amputee Mobility, Health, and Societal Impact.

    SBC: ADARACT            Topic: NIDILRR

    This project is focused on the development of a unique powered prosthetic for transfemoral (above knee) amputees with capabilities that are currently unavailable from similar prosthetics in the market. The powered transfemoral prosthetic utilizes bundles of high-pressure hydraulic artificial muscles for actuation of both the knee and ankle joints. An interest in utilizing the hydraulic artificial ...

    SBIR Phase I 2023 Department of Health and Human ServicesAdministration for Community Living
  10. Implementation and validation of a lung x-ray interferometry imaging system, with applications to COPD, COVID-19 and other lung diseases

    SBC: REFINED IMAGING, LLC            Topic: NHLBI

    AbstractLung diseases ranging from cancer to chronic obstructive pulmonary disease (COPD) affect large numbers of men and women worldwide each year. Current news reports describe the respiratory impact of COVID-19; likewise, the past year has seen extensive coverage of the respiratory problems caused by vaping. Worldwide, lung diseases of all types result in millions of deaths per year at a stagge ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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