Award Data

During Phase I, Management Sciences, Inc. (MSI) proved feasibility of adapting their current technology into a product capable of improving performance resulting in increased efficiency and extended life cycles of heat pumps. The resultant product is a tool named the Heat Pump Sentient (HP-Sentient). The HP-Sentient will improve performance and reduce maintenance costs through aggressive goal-seek ...

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DESCRIPTION provided by applicant Severe infections various types of trauma and other etiologic factors can cause ALI that rapidly morphs into ARDS The incidence of ALI ARDS is around in adults in US alone Despite medical advances and better management through ventilation intervention the mortality is still unacceptably high at This problem is likely to escalate given the a ...

DESCRIPTION provided by applicant Atrial fibrillation AF is the most common diagnosed arrhythmia with the number Americans diagnosed with AF estimated at million and continuing to increase as the population ages Electrical activity during AF is characterized by complex activation patterns that are difficult to map However there is growing evidence that AF is driven by stable sources i ...

DESCRIPTION provided by applicant Lung cancer remains the leading cause of cancer related deaths worldwide Surgical removal of the tumor is the best therapeutic option for patients with non small cell lung cancer yet up to of patients still leave the operating room with deposits of cancer left behind Advances in CAT and PET scans have provided surgeons with helpful radiographic imaging i ...

DESCRIPTION provided by applicant This project will lead to the development of an optimized X ray tube with focal spots that can be placed immediately below and around the multi leaf collimator MLC of a radiotherapy system By steering a focused electron beam e beam on a series of cooled tungsten targets in sequence this system will provide a set of projection images that can be reco ...

DESCRIPTION provided by applicant Alcohol Use Disorder affects of the U S population ages and older and costs society over $ billion per year in direct medical costs accidents and lost productivity Current pharmacotherapy is only modestly effective and has to be used in conjunction with psychosocial treatment Primary care physicians are ill equipped to provide the currently neces ...

DESCRIPTION provided by applicant Duchenne muscular dystrophy is caused by mutations in the dystrophin gene resulting in the loss of the dystrophin glycoprotein complex in skeletal muscle Loss of dystrophin results in reduced sarcolemmal integrity progressive muscle damage and compromised muscle function There is currently no cure and limited treatment options for DMD and all affected child ...

DESCRIPTION provided by applicant Diabetes affects an estimated million people worldwide including more than million Americans Diabetic patients are at risk for a wide array of complications including heart disease kidney disease nephropathy ocular diseases diabetic retinopathy and diabetic foot peripheral neuropathy Fifteen percent of diabetics wil develop a foot ulcer as a ...

DESCRIPTION provided by applicant Taxol paclitaxel is the one of the most widely used chemotherapy agents and is a first line treatment for ovarian breast lung and colon cancer Despite its well documented anti cancer properties taxol is known to cause chemotherapy induced peripheral neuropathy CIPN CIPN affects approximately of all chemotherapy patients and the neuropathic ...