Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Adherence Assessment for Supplements

    SBC: Icagen, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The use of dietary supplements has become increasingly popular in the US, and these supplements are not subject to stringent pre-marketing testing or post-marketing surveillance. More than a third of American adults report using some form of CAM, with total visits to CAM providers each year now exceeding those to primary-care physicians. An estimated 15 million ...

    SBIR Phase I 2006 Department of Health and Human Services
  2. Software to Facilitate DNA Cloning

    SBC: GSL BIOTECH, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): DNA cloning, also known as gene splicing or recombinant DNA technology, is crucial for all aspects of biomedical and biotechnology research. For example, DNA cloning has been of central importance for sequencing the human genome, generating safer vaccines, identifying genes involved in cancer and many other diseases, and producing therapeutic drugs such as insu ...

    SBIR Phase I 2006 Department of Health and Human Services
  3. Simulation-based Dental Training System

    SBC: IDEA INTERNATIONAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I SBIR proposal will yield a prototype of a fully synthetic simulation-based training system to teach proper assessment, diagnosis and treatment of incipient lesions and true dental caries. IDEA International, Inc., in conjunction with the Harvard Dental School and others with experience in the simulation and virtual environment business, will create ...

    SBIR Phase I 2006 Department of Health and Human Services
  4. Retinal Image Enhancement based on the Human Visual System

    SBC: Kestrel Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is to demonstrate a methodology for improving the quality of retinal images taken with standard fundus camera. Kestrel has developed a family of algorithms that perform image retinal enhancement through the implementation of a methods that are inspired from human visual system mechanisms. Standard retinal images often suffer from i ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Treatment of Calcium Nephrolithiasis Sodium Thiosulfate

    SBC: LITHOLINK CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The broad objective of this proposed research is to determine the effect of sodium thiosulfate on kidney stone formation. The drug will initially be studied in a rat model of nephrolithiasis and if the drug is shown to reduce risk of new stone formation we will study the drug in patients with nephrolithiasis. The long term goal is to bring a new therapy for kid ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. Free Form Fabrication of Dental Copings and Restorations

    SBC: Robocasting Enterprises, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this project is the development of a solid freeform fabrication system for producing dental restorations and devices. This system is based on the "robocasting" approach. Robocasting is a solid freeform fabrication technique that uses automated extrusion of colloidal slurries, pastes, inks, etc. to build complicated structures of ceramics and me ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Improvement of RNAi efficacy by blocking RNAi inhibitors

    SBC: SILENTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA Interference (RNAi) promises to become a powerful approach to rational drug design. One significant drawback to RNAi is that its effect on gene expression is rarely 100% potent. This limitation, observed widely, is problematic when a complete cessation of gene expression is desired or required. A major goal of this proposal is to develop targeted strategies ...

    STTR Phase I 2006 Department of Health and Human Services
  8. Technology to access medication label information for severely visually impaired

    SBC: SIXTYSEVEN KILOHERTZ, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop technology that uses the camera function of a cellular phone to read a special graphical code on the label of a prescription medication container. This code would trigger the retrieval of label information, saved on a remote server, which after being run through a text-to-speech engine, would be read aloud to the user through the phone. We ...

    SBIR Phase I 2006 Department of Health and Human Services
  9. Advances in noninvasive, fluid-less alcohol measurements

    SBC: Trutouch Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of TruTouch Technologies, Inc. is to develop a new, more accurate, and cost-effective technology for noninvasive measurement of alcohol in human subjects. The TruTouch noninvasive measurement device offers the promise of reduced measurement time, elimination of safety concerns regarding handling of bodily fluids, and simplification of the alcohol ...

    SBIR Phase I 2006 Department of Health and Human Services
  10. Hair Ethyl Glucuronide as a Long Term Alcohol Biomarker

    SBC: United States Drug Testing Laboratories, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a need for a highly sensitive (> 90%) and specific (> 90%) long term biomarker to both detect and monitor individuals who are heavy users of alcohol. Monitoring short term (3-5 days) alcohol use and abuse by impaired professionals by using urine ethyl glucuronide (EtG) has been shown to be both sensitive and specific (> 90%). Recently evidence has emer ...

    SBIR Phase I 2006 Department of Health and Human Services
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