Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Enhancing the immunogenicity of idiotypes for therapy of Non-Hodgkin's lymphoma

    SBC: ADVAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Non-Hodgkin's Lymphoma (NHL) is characterized by an indolent clinical course with a median survival of 6- 10 years. The incidence of NHL in the US increases by about 2.5% per year. Clearly, there is a national need for improved therapies for this malignancy. Idiotype-based clinical trials for minimal residual disease of follicular NHL have shown increased disea ...

    STTR Phase I 2006 Department of Health and Human Services
  2. LOW-COST AFFINITY SYSTEM FOR PREPARATION OF PLASMA/SERUM FOR BIOMARKER ANALYSIS

    SBC: APD LIFE SCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a disposable, affinity-based capillary tube [AffiTip] that is capable of removing 99% of the interfering bulk protein from < 5 :L of undiluted plasma within 2 minutes for use prior to analysis for biomarkers [specific compounds that link mechanism of action and clinical effectiveness]. The product ultimately will be introduced at a sale price [p ...

    SBIR Phase I 2006 Department of Health and Human Services
  3. Sphingosine Kinase Inhibitors as Anti-IBD Agents

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this program is to develop novel inhibitors of human sphingosine kinase (SK) that are effective as therapeutic agents. Because of its critical role in sphingolipid metabolism, we have focused on SK as an innovative molecular target for the development of new drugs for the treatment of Inflammatory Bowel Diseases (IBDs). Sphingolipids are being incre ...

    SBIR Phase II 2006 Department of Health and Human Services
  4. Anti-Atherosclerosis Agents Targeting Sphingosine Kinase

    SBC: Apogee Biotechnology Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Principal Investigator/Program Director: French, Kevin J. Abstract: The long-term goal of this program is to develop inhibitors of human sphingosine kinase (SK) that are effective as therapeutic agents. Because of its critical role in sphingolipid metabolism, we have focused on SK as an innovative molecular target for the development of new drugs for the treatm ...

    SBIR Phase I 2006 Department of Health and Human Services
  5. Development of a Wearable Seizure Warning Device

    SBC: CHATTEN ASSOC., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): In spite of advances in medical and surgical treatment, there are at any one time estimated to be some 350,000 individuals in this country whose seizures occur without warning and result in some combination of disordered thinking, impaired consciousness, or loss of motor control. Epileptologists and patients alike have long understood the magnitude of this prob ...

    SBIR Phase I 2006 Department of Health and Human Services
  6. Bathing aids palliative cancer care & aging-in-place

    SBC: AUGMENTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose developing bathing assistance technologies that are closely related at the device level for two very distinct, but important and underserved populations of potential users: 1) bedroom bathing for people with fragile skin receiving palliative care for advanced cancers and 2) ground floor bathing for elderly mobility impaired people who cannot afford t ...

    SBIR Phase I 2006 Department of Health and Human Services
  7. Disposable sensor for on-line measure of urea clearance in effluent dialysate

    SBC: AURA NANOTECHNOLOGY, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): A key need for urea monitoring is a simple and disposable device that can be easily integrated with existing hemodialysis (HD) technology. This proposal aims to demonstrate the feasibility of accurate on-line urea clearance monitoring using nanoengineered colorimetric films deposited directly on the inside surface of short lengths of standard dialysis tubing. T ...

    SBIR Phase I 2006 Department of Health and Human Services
  8. Peptide drugs against influenza virus

    SBC: Autoimmune Technologies, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Influenza virus is one of the most important human pathogens accounting for widespread morbidity and mortality. Influenza virus is currently classified as a NIAID Biodefense Category C priority pathogen, a status that may be upgraded due to the recent emergence of a highly virulent strain of avian influenza virus in Thailand, Vietnam, North Korea and other Asi ...

    STTR Phase I 2006 Department of Health and Human Services
  9. Development of molecular diagnostic assays for systemic autoimmune diseases

    SBC: Autoimmune Technologies, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): We aim to produce a significantly improved diagnostic system for autoimmune, rheumatologic disease. Similarities between autoimmune diseases and HIV-induced diseases led us to look for a retrovirus involved in autoimmune disease. We found a retrovirus, human intracisternal A-type particle (HIAP), in Sjogren's syndrome patients. Subsequently we found evidence in ...

    STTR Phase I 2006 Department of Health and Human Services
  10. Tendrils: A Multimedia Intervention for Women's Sexual Dysfunction after Cancer

    SBC: Digital Science Technologies LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Long-term Objectives Aims: Sexual dysfunction is the most common long-term consequence of cancer treatment, affecting half of survivors of breast and gynecological cancer and many women treated for other cancers. Yet, few women get the help they need for sexual problems. Our primary objective is to develop and evaluate a multimedia intervention program for wome ...

    STTR Phase I 2006 Department of Health and Human Services
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