Award Data

Advanced Cooling Technologies, Inc. (ACT), supported by Hamilton Sundstrand, proposes to develop a shock and vibration tolerant Capillary Two-Phase Loop for military vehicle applications. The proposed capillary two-phase loop differs from the traditional loop heat pipes and capillary pumped loops in the evaporator design, which provides inherent tolerance to shock and vibration. Two additional fea ...

The objective of this proposal is to demonstrate the feasibility of producing exchange-coupled magnets with a mixture of Sm2Fe17Nx and alpha double prime-iron nitride powders as starting materials. Advanced Materials Corporation (AMC), together with Georgia Institute of Technology propose to produce these powders with the use of a fluidized bed reactor and consolidate mixtures of these powders uti ...

DESCRIPTION (provided by applicant): Non-Hodgkin's Lymphoma (NHL) is characterized by an indolent clinical course with a median survival of 6- 10 years. The incidence of NHL in the US increases by about 2.5% per year. Clearly, there is a national need for improved therapies for this malignancy. Idiotype-based clinical trials for minimal residual disease of follicular NHL have shown increased disea ...

A complementary, theoretical and experimental effort to design and verify high-lift, low pitching-moment airfoils for VTOL UAVs is proposed. In Phase I, an accurate, rapid, test capability will be validated over the range of Reynolds numbers from 50,000 to 500,000 by investigating the E 387 airfoil, the low Reynolds number calibration standard, in The Pennsylvania State University Low-Speed, Low- ...

DESCRIPTION (provided by applicant): We will develop a disposable, affinity-based capillary tube [AffiTip] that is capable of removing 99% of the interfering bulk protein from < 5 :L of undiluted plasma within 2 minutes for use prior to analysis for biomarkers [specific compounds that link mechanism of action and clinical effectiveness]. The product ultimately will be introduced at a sale price [p ...

DESCRIPTION (provided by applicant): The goal of this program is to develop novel inhibitors of human sphingosine kinase (SK) that are effective as therapeutic agents. Because of its critical role in sphingolipid metabolism, we have focused on SK as an innovative molecular target for the development of new drugs for the treatment of Inflammatory Bowel Diseases (IBDs). Sphingolipids are being incre ...

DESCRIPTION (provided by applicant): Principal Investigator/Program Director: French, Kevin J. Abstract: The long-term goal of this program is to develop inhibitors of human sphingosine kinase (SK) that are effective as therapeutic agents. Because of its critical role in sphingolipid metabolism, we have focused on SK as an innovative molecular target for the development of new drugs for the treatm ...

Though ladar and stereo have received far more attention for UGV navigation use, radar offers some unique benefits. Many radar systems have the ability to partially penetrate thin vegetation, fog, smoke, and other obscurants while detecting hidden solid obstacles. Also, some systems provide useful information in addition to range; for example, Doppler radars measure target relative velocities as w ...

The Third Generation Fast Steering Mirror (3GFSM) is based on a scalable design and uses high performance, high bandwidth electromagnetic (HBE) actuators. Mirror apertures are scalable from one inch to five inches and can be round or elliptical. The HBE actuators are more efficient than voice coil actuators and can be configured to support large displacement angles. Much lower mirror profiles ...

Chatten Associates proposes a research and development plan to improve the head-aimed vision system for remote operation of unmanned ground vehicles that was demonstrated in Phase I. We will deliver a number of head-aimed vision systems to ARDEC Picatinny for their use in test and evaluation. We will specifically support a test of high-speed tele-operation of an Ackermann-steered vehicle. We will ...