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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

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  1. Protein Qspec: An Improved Method for Rapid Characterization of Protein Aggregates in Biologic Drugs for Increased Quality and Safety

    SBC: OPTOFLUIDICS, INC.            Topic: 90201

    Optofluidics will develop Protein Qspec, a new particle analysis QC instrument designed to characterize protein aggregates in biologic drugs. The primary concern for this class of therapeutics is that they can elicit an immune response from patients who develop anti-drug antibodies which can eliminate the therapeutic benefit. The presence of particulate matter, in these therapeutics (e.g. shed gla ...

    SBIR Phase I 2016 Department of CommerceNational Institute of Standards and Technology

  2. A PORTABLE IMAGING SYSTEM FOR NONDESTRUCTIVE EXAMINATION OF NUCLEAR POWER PLANT COMPONENTS

    SBC: T P L, INC            Topic: N/A

    THE DIFFICULTY IN PREDICTING STRUCTURAL DEGRADATION RATES FOR NUCLEAR POWER PLANT COMPONENTS DUE TO CORROSION AND OTHER FACTORS HAS LED TO THE NEED FOR COSTLY, TIME CONSUMING INSPECTIONS AND INCREASED COST FROM INTENTIONALLY OVERDESIGNED COMPONENTS. THE SITUATION INDICATES A SERIOUS, UNMET NEED FOR A SIMPLE BUT ACCURATE SYSTEM FOR REAL- TIME, IN SITU, NONDESTRUCTIVE ANALYSIS OF NUCLEAR POWER PLANT ...

    SBIR Phase II 1994 Nuclear Regulatory Commission
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