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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Assay optimization and adaptation for a customized meter development

    SBC: GlucoSentient, Inc            Topic: NIAID

    Invasive fungal infectionsIFIcaused by ubiquitous mold and yeast is a common cause of negative health outcomes for immunocompromised patientsincluding patients undergo solid organ transplantSOTand hematopoietic stem cell transplantHSCTregularly leading to events such as organ failure or deathCurrent methods for screening IFI rely on laboratory tests that require specialized equipment and professio ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Wireless Compatible Digital Train Line (WiDTL) for Passenger Type Vehicles in a Train Consist

    SBC: Sharma & Associates, Inc.            Topic: 151FR1

    The Next Generation Equipment Committee (NGEC) developed a standard for specifying the use of an Ethernet based digital train line (DTL) network to replace the COMM line for passenger trains. These specifications are PRIIA 305‐919 Digital Train Line Hardware and PRIIA 305‐920 Digital Train Line Software. The intent Is to eventually allow for the improvement of passenger train control. DTL spec ...

    SBIR Phase II 2017 Department of Transportation
  4. A Metabologenomics Platform for Large Scale High Throughput Natural Product Discovery

    SBC: Microbial Pharmaceuticals, Inc.            Topic: NCCIH

    ABSTRACT The estimates of natural product producing gene clusters within the genomes of microorganisms are far greater than the number of known natural products indicating that there is a wealth of untapped molecules within these organisms that offer huge potential as leads for new medicines Unfortunately the prevailing paradigms for natural product discovery are ill suited for accessing this ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Assembled Porous Silica Membranes for Biomolecule SPE

    SBC: ADVANCED MATERIALS TECHNOLOGY, INC.            Topic: 400

    Abstract Life sciences research and other critical bioanalytical applications would strongly benefit from faster and higher efficiency sample preparation processes Sample preparation before high resolution analytical methods such as HPLC or LC MS can require effort and cost nearly equivalent to the actual sample analysis and data reduction Often sample preparation for proteomic glycoproteom ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. A rapid and portable test for home monitoring of phenylalanine levels by patients with phenylketonuria using a blood glucose meter

    SBC: GlucoSentient, Inc            Topic: NICHD

    Project Summary Abstract Phenylketonuria PKU is a serious inborn metabolic disorder affecting out of every children born in the U S annually Characteristic effect of PKU is the impaired capability of the body to convert the amino acid phenylalanine Phe to tyrosine and as a result Phe level is elevated in the blood stream While Phe is required for normal growth and brain developm ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Developing an integrated sorting and single cell analysis tool for the analysis of rare T Cells subsets in Autoimmunity

    SBC: IsoPlexis            Topic: R

    Autoimmune disease AD affects up to million Americans which costs approximately $ billion on health care annually and accounts for one of the leading causes of death in women T cells and cytokine function play an important role in autoimmune diseases such as Type Diabetes Multiple Sclerosis Rheumatoid Arthritis RA and Systemic Lupus Erythematosus SLE The most successful auto i ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Optimizing NGF for Topical Treatment of Glaucoma

    SBC: HUMAN CELL CO            Topic: N

    Glaucoma is one of the leading causes of blindness in the world This chronic and progressive optic neuropathy is characterized by loss of axons of the retinal ganglion cells RGC that constitute the optic nerve Reduction of elevated intraocular pressure the only modifiable causative factor slow the onset and progression of the disease yet no treatment is available to restore o ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Technology Enabled Mental Health Intervention for Individuals in the Criminal Justice System A

    SBC: Jail Education Solutions, Inc.            Topic: 104

    In the United States over million people are incarcerated While these numbers are alarming even more distressing is the rapid growth in the number of mentally ill individuals caught in this system Within any given year approximately of females and of males in jail will experience a mental health problem This results in the criminal justice system serving as a de facto mental ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Recombinant Prothrombin Therapy for Hemorrhage

    SBC: HUMAN CELL CO            Topic: NHLBI

    Uncontrolled bleeding remains one of the leading causes of trauma induced death Current treatment recommendations focus on fresh frozen plasma and blood cell transfusions which do not seem to be effective Over the last few years these is increasing use of prothrombin complex cencentrate to treat hemorrhage associated coagulapathy which is effective but induces disseminated intravascular coagula ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health

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