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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. AN INTERACTIVE, NATIONWIDE GEOGRAPHICAL INFORMATION SYSTEM TO ADMINISTER HIGHWAY ROUTE DESIGNATIONS FOR THE TRANSPORTATION OF HAZARDOUS MATERIALS

    SBC: Aegis Information Systems            Topic: N/A

    IN ACCORDANCE WITH THE HAZARDOUS MATERIALS TRANSPORTATION UNIFORM SAFETY ACT OF 1990 (HMTUSA), DOT IS NOW REQUIRED TO CREATE A CENTRALIZED DATABASE OF STATE-DESIGNATED HAZARDOUS MATERIAL HIGHWAY ROUTES. DOT IS ALSO RESPONSIBLE FOR PERIODICALLY UPDATING AND PUBLISHING A LIST OF CURRENLY EFFECTIVE HAZARDOUS MATERIALS HIGHWAY ROUTE DESINGATIONS IN THE FEDERAL REGISTER. IN RESPONSE TO THIS NEED, AEGIS ...

    SBIR Phase II 1995 Department of Transportation
  2. Efficient Lossless EEG Compression Engine

    SBC: Alacron, Inc.            Topic: N/A

    We will develop an advanced lossless data compression engine for EEG, for use in telephone EEG transystems and digital EEG recording systems. While useful in rural and remote setting without ready acelectroencephalographers, and for home monitoring in selected patients with epilepsy and sleep distuavailable EEG telephone transmission systems restrict the number of channels of EEG transmitted andof ...

    SBIR Phase I 1995 Department of Health and Human Services
  3. 26-Hydroxycholesterol--Therapy for Ctx and Restenosis

    SBC: ALBANY MOLECULAR RESEARCH, INC.            Topic: N/A

    26-Hydroxycholesterol is a naturally occurring metabolic product derived from cholesterol. Recent isuggest that this metabolite plays a role as a feedback inhibitor of cholesterol synthesis and may bregulation of LDL receptors. The absence of 26-hydroxycholesterol has been postulated to be the molegenetic disease cerebrotendinous xanthomatosis. The discovery that this compound is produced in vascs ...

    SBIR Phase I 1995 Department of Health and Human Services
  4. Developing Methods for Complex Sample Surveys

    SBC: ANALYSIS & SIMULATION, INC.            Topic: N/A

    EIFACS (Expanded Integrated Facility for Analysis of Complex Surveys) will provideepidemiologists at NIAAA and other researchers with the capability to perform valid multivariatestatistical analyses on survey data involving complex sampling designs in an easy-to-use windowed PCenvironment. Variance estimation will utilize Taylor series linearization, jackknife, and, possibly,bootstrap techniques. ...

    SBIR Phase II 1995 Department of Health and Human Services
  5. Nonradioactive Receptor Binding Assays

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    The use of biotin labeled ligands in receptor binding assays will be used as a substitute for radioHigh affinity biotinylated ligands are used in immunochemistry studies but are not generally employebinding experiments. Biotinylated ligands also have high affinities for the proteins avidin and streproteins can be coupled with various enzymes which catalyze spectrophotometric, fluorometric, or ched ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. PORTABLE BALLOON PUMP DRIVER

    SBC: Amnis Corporation            Topic: N/A

    CIRCULATORY ASSIST DEVICES ARE NEEDED FOR IMMEDIATE TEMPORARY TREATMENT OF ACUTE MYOCARDIAL INFARCTION AND FOR SOME POSTCARDIOTOMY PATIENTS. SINCE MORE THAN 30 YEARS AGO, THE EFFORTS OF A NUMBER OF RESEACHERS AND CLINICIANS HAVE RESULTED IN THE NOW WIDELY USED COUNTERPULSATION INTRA-AORTIC BALLOON PUMPING (IABP), WHICH INCREASES MYOCARDIAL OXYGEN UPTAKE AND CORONARY PERFUSION, AND REDUCES LOAD ON ...

    SBIR Phase II 1995 Department of Health and Human Services
  7. Purge System for Implanted Blood Pumps

    SBC: Amnis Corporation            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Health and Human Services
  8. Detection of Gene Amplification in Human Breast Tumors

    SBC: AMPLICON CORPORATION            Topic: N/A

    Cytogenetic studies indicate the presence of novel amplified DNAs specific for human breast cancersMYC, neu and PRAD1 have been found amplified in 5-40% of breast cancer biopsies and cell lines, andare amplified less frequently. Laborious approaches to clone DNA from the cytogenetic manifestationsamplification have not proven to be efficient or simple means to novel oncogenes. RDA or representatan ...

    SBIR Phase I 1995 Department of Health and Human Services
  9. Facilitating The Diagnosis of Angelman Syndrome

    SBC: Tiranoff Productions LLC/GeneticaLens            Topic: N/A

    The Angelman Syndrome video project will address a deficit which now exists in the health care systone genetic disorder thought to be rare. Two comprehensive discs in the CD-ROM and CDI formats willwill show symptoms and behaviors of AS individuals, allowing interaction by the user. Subject will bown environments to maximize normal behavioral characteristics. A second linear documentary videotappr ...

    SBIR Phase I 1995 Department of Health and Human Services
  10. New Assay for Erythrocyte Hematopoietic Activity

    SBC: Bacus Laboratories, Inc.            Topic: N/A

    Our long term objective is to design and develop a prototype instrument for automated reticulocyteerythrocyte maturation determination, based on the latest technology in image cytometry, to increaseaccuracy, and reliability of bone marrow activity assessments. Evaluation of bone marrow activity habecome important in clinical and research medicine as shown by the marked increase in the number ofreq ...

    SBIR Phase I 1995 Department of Health and Human Services
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