Award Data

DESCRIPTION provided by applicant This Phase II SBIR grant is a follow up to the Phase I SBIR grant andquot Computerized Screening for Comorbidity in Adolescents with Substance or Psychiatric Disorders andquot During Phase I parent and adolescent self administered computerized versions of the psychiatric interview the Kiddie Schedule for Affective Disorders and Schizophrenia KSADS were de ...

DESCRIPTION provided by applicant Aptamer Based Detection of Cardiac Biomarker Glycosylation States Using APT SNAP Arrays PIs Christopher L Warren and Mary S Ozers The presence of cardiac related biomarkers in patient biospecimens can provide important insight into diagnosis of cardiovascular disease its progression and optimal therapies for treatment Most of the cardiac biomarkers in cli ...

DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

DESCRIPTION provided by applicant CRM is an inactive form of diphtheria toxin that when conjugated to a vaccine antigen enhances immunity to generate long lasting vaccination against the antigen Conjugate vaccines containing CRM are common and there are currently seven CRM containing conjugate vaccines on the market The top selling vaccine the CRM containing conjugate vaccine P ...

DESCRIPTION provided by applicant Primorigen Biosciences R Project Abstract Primorigen will use SBIR funds to develop a paradigm changing technology for expansion and directed differentiation of human pluripotent stem cells hPSCs using a novel peptide that dramatically reduces costs by amplifying the impact of endogenous growth factors and minimizing the need for exogenous growth factors Th ...

The primary goal of this proposed work is to develop a long wavelength infrared (LWIR) colloidal quantum dot (CQD)-based focal plane array (FPA) and show its feasibility when used in a camera system and a hyperspectral imaging system. Phase I results cumulated in the first-ever synthesis of photoresponsive LWIR CQDs and CQD-based photodetectors at the single device level operating at room temperat ...

In this Phase II SBIR program, Illinois Applied Research Associates will design, manufacture, and test a 1.06 um optimized Linear Mode (LM) avalanche photodiode (APD) array. The array will be electrically and optically characterized and will be tested for environmental and application constraints for integration into terrestrial and space based applications. The ability to operate in linear mode ...

DESCRIPTION provided by applicant Pattern recognition PR myoelectric control systems can dramatically improve an amputee patientandapos s control of a powered prosthesis but they have not been made commercially available Coapt LLC is a start up stage company that has initiated a controlled commercial release of PR myoelectric control for the benefit of upper limb amputees The controlle ...

DESCRIPTION provided by applicant Cardiomyopathy has various forms including hypertrophic cardiomyopathy HCM in prevalence could cause sudden cardiac death in athletes Dilated Cardiomyopathy DCM in prevalence results in an enlarge left ventricle Arrhythmogenic Right Ventricular Dysplasia Cardiomyopathy ARVD C in prevalence causes cardiac fibrosis Yearly over $ ...

DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...