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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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BIOMARKER FOR EARLY DETECTION OF CHRONIC KIDNEY DISEASE
SBC: SEQUELA, INCORPORATED Topic: NIDDKDESCRIPTION (provided by applicant): There are an estimated 26 million Americans with early chronic kidney disease (CKD). Early diagnosis and treatment are the only cost-effective means to reverse this growing problem. NIH recognizes the challenge to diagnose CKD early during its initiation and development phases in order to prevent further renal damage, reduce cardiovascular risk, and minimize th ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Enhancing mammalian glycoprotein production in the baculovirus expression vector
SBC: PARATECHS CORP Topic: NIGMSDESCRIPTION (provided by applicant): The baculovirus expression vector system (BEVS) is a proven, powerful and versatile method of eukaryotic protein expression. It is used to produce vaccines, diagnostics, and biologically active proteins for a multitudeof research projects. Like all expression systems, however, BEVS has its disadvantages. One is the fact that expression is short-lived due to vir ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
FastFES Neural Prothesis for Stroke Ambulation and Rehabilitation
SBC: CUSTOMKYNETICS, INC. Topic: NICHDDESCRIPTION (provided by applicant): This FastTrack SBIR proposal aims to disseminate a Functional Electrical Stimulation (FES) technology for stroke ambulation and neuromotor rehabilitation. The FastFES paradigm integrates two rehabilitation approaches,fast-paced treadmill walking and FES, in a manner that has been shown to both improve gait kinematics when the stimulation is active and to impro ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Counterpulsation Device with Integrated EKG System for Chronic Partial Circulator
SBC: SCR, INC. Topic: NHLBIDESCRIPTION (provided by applicant): Heart failure (HF) remains one of the largest unsolved problems in health care today and continues to increase in incidence and cost ( 34.8 billion in US in 2008). Prognosis remains limited especially in patients with advanced heart failure. Transplantation is often the best option for patients with advanced HF whose hearts are not recoverable but is limited by ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel Therapeutic for Alzheimer' Disease
SBC: CoPlex Therapeutics, LLC Topic: NIADESCRIPTION (provided by applicant): Traditional approaches to drug development for Alzheimer's disease are becoming increasingly expensive and in many cases disappointingly unsuccessful. Based on preliminary in vitro and in vivo studies we have identifieda novel lactam derivative of the commonly prescribed 1,4 dihydropyridine calcium channel blocker nifedipine (1-acetyl-2,4- dimethylbenzo[c] ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Long-Term Broad-Spectrum Prevention of Implant-Related Infections
SBC: Biomedical Development Corporation Topic: NIADESCRIPTION (provided by applicant): Deep wound infection following total joint arthroplasty is a devastating complication for physician and patient, a leading cause of morbidity, and a significant economic burden to the healthcare system. With an aging population and increased life expectancies, the number of arthroplasties is expected to rise dramatically over the next 20 years. The growing numb ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Delayed Tolerance Induction in Living Related Donor Renal Transplant Recipients
SBC: REGENEREX, LLC Topic: NIAIDDESCRIPTION (provided by applicant): We have developed a protocol that reproducibly induces transplantation tolerance in individuals undergoing a living related donor kidney transplant. Three subjects have been off all immunosuppression for 10 months, 2 months, and 1 month respectively and have remained chimeric with stable renal function. Two additional chimeric subjects are in various stages of ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Development of a Plasma Biomarker of Alzheimer's Disease
SBC: SCOUT DIAGNOSTICS Topic: NIEHSDESCRIPTION (provided by applicant): The major barriers to preventing or treating Alzheimer's disease (AD) are its unknown pathogenesis/etiology and the lack of an objective, sensitive and specific biomarker of the disease, particularly at the early stageswhen therapeutic interventions would likely have the greatest efficacy. The basic hypothesis of this application is that plasma levels of a ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Transdermal Naltrexone for Opiate Addiction and Alcoholism
SBC: ALLTRANZ, INC. Topic: NIDADESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction. Naltrexone (NTX), an opioid antagonist, is currently used in oral tablet form to help maintain opio ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Delivery of Polyphenols in Gum for Treatment of Gingivitis
SBC: FOUR TIGERS, LLC Topic: NIDCRDESCRIPTION (provided by applicant): Periodontitis represents a polymicrobial disease, in which a complex microbial ecology that matures in biofilms in the subgingival sulcus triggers a chronic immune-inflammatory lesion that destroys soft and hard tissues of the periodontium. Despite the great improvement in oral health in recent years, gingivitis and periodontal disease remain prominent and aff ...
STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health