Award Data

The focus of this project is to develop a low-cost, wearable, easy to use, continuous socket/suspension monitoring system (SSMS) that tracks the relative displacement between the amputees’ residual limb and their socket or pistoning through the use of magnetic sensors. To do this, the project (1) designs and constructs the SSMS and demonstrates its capability through a bench top experiment; (2) ...

This project develops a mobile device and/or web-based coaching tool that provides evidence-based therapeutic strategies for children with anxiety disorders with the goal to improve independence and participation in daily activities. Anxiety disorders are among the most common childhood mental health diagnoses with lifetime prevalence rates ranging from 15% to 20%. Additionally, anxiety disorders ...

The goal of this project is to provide children with visual disabilities accessible technology that will enhance their community living and participation in an educational setting. The main objective is to give these children access to visual images through added description, while improving their literacy skills through a collaborative process with their peers without visual disabilities. The cus ...

This proposal details the development of UroSeqS as a genetic cytology test to extend the utility of routinely collected urine specimens to the detection of recurrent bladder cancer UroSeqS is a genetic cytology assay that achieves sensitivity and specificity through identifying DNA mutations causative of cancer from routinely collected clinical specimens An innovative approach is used toanalyz ...

Current standardized neuropsychological tests are based on decades old paper and pencil methods They lack reliability sensitivity specificity repeatability and require trained neuropsychologists to administer them Their administration in clinical and research settings result in high cost complexity and inconsistent results There is a need and a commercial opportunity for an extensible co ...

A Rapid Paper Strip Nucleic Acid Test for the Point of Care Detection of Zika virus CrossLife Technologies Inc Project Summary Abstract There are unmet needs for nucleic acids new diagnostics that can be applied at the point of care to detect Zika Virus ZIKV infections A highly sensitive simple paper strip molecular test that detects ZIKV at the point of care will be developed The target seq ...

Project Summary Monoclonal antibodies mAbs are a well validated drug platform with exquisite specificity diversity and potency They offer the lowest risk class of drug for development through licensure and offer great potential for addressing emerging and re emerging infectious diseases To be prepared as threats like Ebola EBOV Marburg MARV and Zika viruses continue to emerge or re em ...

Malaria caused by Plasmodium vivax threatens over billion people globally and sickens tens of millions annually Radical cure for P vivax malaria includes therapy aimed both at the acute attack blood schizontocidal and against future attacks hypnozoitocidal The only hypnozoitocide available are aminoquinolines such as primaquine or tafenoquine However clinicians often do not prescribe ...

PROJECT SUMMARY The aim of this proposal is to develop a rapid low cost and easy to use POC diagnostic test for Zika virus ZIKV ZIKV is an emerging mosquito borne Flavivirus that has gained global attention due to new evidence that it is linked to birth defect microcephaly Additionally health experts are also concerned about the link between the virus and Guillain Barr syndrome GBS Pres ...

Immune mediated diseases such as type diabetes T D multiple sclerosis rheumatoid arthritis and systemic lupus erythematosis are reaching epidemic proportions in the US T D affects an estimated million Americans with more than new patients diagnosed annually resulting in roughly $ B in health care costs in the US each year T D is an autoimmune disease characterized by effector ...