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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A Quantitative Non-destructive Residual Stress Assessment Tool for Pipelines

    SBC: Generation 2 Materials Technology Llc            Topic: 111PH2

    There exists a wide-range need in both industry and government for quantitative residual stress measurements. Generation 2 Materials Technology LLC (G2MT) will collaborate with partners from industry and government to calibrate and commercialize the eStress system to assess residual stress from mechanical damage and re-rounding. The industrial members, consortiums, and government laboratories who ...

    SBIR Phase II 2012 Department of Transportation
  2. A Low Cost, Accurate, and Portable Detection Method for Contaminant Levels in Foo

    SBC: DIAGTRONIX, INC.            Topic: FDA

    DESCRIPTION (provided by applicant): The U.S. CDC estimates that each year roughly 1 in 6 Americans (or 48 million people) gets sick, 128,000 are hospitalized, and 3,000 die of foodborne illnesses. The costs in lost productivity and increased health carecosts are enormous, in addition to the consequences to individuals and families from missed work and schooling, disrupted family life, and pain an ...

    SBIR Phase I 2012 Department of Health and Human Services
  3. Whole-brain fluorescence and brightfield imaging at single-cell level

    SBC: DMetrix, Inc            Topic: NIA

    DESCRIPTION (provided by applicant): The goal of this project is to develop an open and flexible imaging platform capable of rapid, 0.5- 5 m pixel resolution image capture of large-area histology sections (up to 125 mm by 175 mm), in brightfield and by epi-fluorescence optical sectioning. The project involves state-of-the- art instrumentation development coupled with application programming inter ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Evaluation and Production of a Multivalent Adenoviral Plague Vaccine

    SBC: NORWELL, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The final objective of this Phase II SBIR is to complete preclinical studies of a trivalent adenoviral vaccine against plague in preparation for human clinical trials. The plague vaccine project was selected in responseto the growing concern surrounding the organism's possible use in a terrorism event. The NIAID and CDC, in response to this threat, has cla ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Development of RLIP76 protein as a Radiation Countermeasure

    SBC: TERAPIO            Topic: NIAID

    DESCRIPTION (provided by applicant): There remains a critical need for medicines that can counteract the toxic effects of radiation exposure. Terapio is developing a recombinant protein, RLIP76, for use as a radioprotectant for workers, military personnel, or civilians that are either in imminent danger of radiation exposure, or have already been exposed. In research carried out at the Unive ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Flat Panel X-ray Sources for Digital Breast Tomosynthesis System


    DESCRIPTION (provided by applicant): X-ray mammography continues to be the primary tool for breast cancer screening and plays an important role in the diagnosis and management of breast cancer. However, the difficulty in resolving overlapping structures ina 2-D projection image leads to reduced sensitivity. A number of research groups and companies are developing dedicated breast tomographic syste ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. 3D Tracking for OCT Image Fusion in Gynecological Diagnosis

    SBC: Biotex, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The goal of this Phase II SBIR project is to continue development of an exciting platform based on integration of optical coherence tomography acquisition with real-time 3D spatial localization. In Phase I, in the context of gynecological diagnostic imaging, we demonstrated hardware and software for prototype image fusion between colposcopic/intravaginal imagin ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Novel Cyclofructan Based Chiral Selectors for Pharmaceutical Purification

    SBC: AZYP, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): The separation of enantiomers (i.e. chiral separations) is of great importance in the development of safe chiral pharmaceuticals and the study of chiral biological toxins and carcinogens. For pharmaceutical compounds that are chiral, usually one enantiomer (either the right or left-handed version) is the drug, while the other half causes side effects, differen ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. Development of the PathLock biasing caster system Phase 2


    DESCRIPTION (provided by applicant): The importance of reducing the incidence of secondary injuries related to manual wheelchair (MWC) propulsion is undisputed. Based on several research studies, approximately 50% of manual wheelchair users (MWU) report symptoms of repetitive strain injury (RSI) related to the demand on the upper extremity during propulsion and transferring tasks. A substantial e ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. GI-Safer Formulation of Indomethacin for use in Preterm Neonates

    SBC: PLx Opco Inc.            Topic: NICHD

    DESCRIPTION (provided by applicant): This application is for a SBIR Phase II grant. One of the major causes of morbidity and mortality of low birth weight neonates relates to injury, inflammation, perforation and obstruction of the lower GI tract, which can be manifest in the related diseases Necrotizing Enterocolitis (NEC) and Spontaneous Intestinal Perforation (SIP). These digestive diseases, wh ...

    SBIR Phase II 2012 Department of Health and Human Services

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