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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Electronically Controlled Pneumatic Brake System Emulator Development

    SBC: Sharma & Associates, Inc.            Topic: 121FR2

    Migration of the vehicle fleet from the current, pneumatic-only, automatic air brake (AAB) system to ECP presents a significant challenge due to the systems’ inherent operational incompatibility. This project will investigate the feasibility of devices that can help to ease this transition by allowing ECP equipped cars to operate in a conventionally braked train, as well as devices to permit con ...

    SBIR Phase I 2012 Department of Transportation
  2. Soluble high-affinity T cell receptors prevent MRSA lethality

    SBC: IMMUVEN, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Methicillin resistant Staphylococcus aureus (MRSA) and methicillin sensitive S. aureus (MSSA) are highly significant human health threats that are responsible for a range of diseases. Recently, the CDC and colleagues reported that MRSA are the most significant causes of serious infections and infectious disease deaths in the United States. A major factor involv ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Non-invasive Assessment of Skeletal Muscle Loss in Cancer Patients

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: NIAMS

    DESCRIPTION (provided by applicant): Abstract The long-term objective of this research is to develop a non-invasive approach for assessment of de novo 3MH production in cancer patients early in the course of the disease as a way of assessing which patients are at high risk for future development of skeletal muscle atrophy. The approach is based on: 1) the known increase in de novo production ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Cross-platform remote monitoring technologies to monitor and improve adherence to

    SBC: LEAP OF FAITH TECHNOLOGIES, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Medication nonadherence is a costly healthcare problem, adding 177 billion annually to the nation's healthcare expenditures. Three out of four Americans do not take their medicine as prescribed, and the ramifications affect virtually every aspect of the health care system. It is called America's other drug problem for good reason. Nonadherence issues ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Cerebral Aneurysm Clipping Training Simulator using Virtual Reality and Haptics

    SBC: IMMERSIVETOUCH, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): IMMERSIVETOUCH(R) VIRTUAL REALITY-HAPTIC NEUROSURGERY SIMULATOR: CRANIOTOMY AND ANEURYSM CLIPPING Founded by principal investigator Dr. Pat Banerjee, ImmersiveTouch,(R) Inc. (Westmont, Illinois) is a small business thatdevelops fully immersive, visio-haptic virtual reality software engineered into a hardware workstation for the training of surgical residents. T ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Novel drug VS-105 for treatment of diabetic nephropathy

    SBC: Vidasym, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): Twenty-six million people in America have chronic kidney disease (CKD). Diabetes is by far the leading cause of CKD (diabetic nephropathy), accounting for 44% of new cases of dialysis (in 2005). Current treatments including ACE inhibitors for CKD patients mainly focus on managing symptoms and disease complications. Despite the various treatments available, the ...

    STTR Phase I 2012 Department of Health and Human Services
  7. Feasibility of Pediatric Contrast Sensitivity Test

    SBC: Precision Vision, Inc.            Topic: NEI

    DESCRIPTION (provided by applicant): This STTR project develops and assesses a new clinical test of visual contrast sensitivity that will work on infants and uninstructable children nd adults. This Stripe Card Contrast Sensitivity (SCCS) test would be useful in quantitatively describing the visual function of patients with a range of visual disorders, in planning and following treatments and inter ...

    STTR Phase I 2012 Department of Health and Human Services
  8. A Force-controlled Probe Based Platform for Single Cell Biomolecular Delivery

    SBC: INFINITESIMAL, LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): Application of nanotechnology in medicine, nanomedicine, has provided numerous emerging opportunities in healthcare, particularly given ever increasing demand for in vitro toxicology and diagnostics towards personalized medicine. With increasing demand for personalized medicine, pharmaceutical companies strive in taking advantage of the potential of nan ...

    STTR Phase I 2012 Department of Health and Human Services
  9. A blood test to predict sudden death risk

    SBC: 3PrimeDx, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): ROS Technologies, Inc, is a medical diagnostics company developing a blood test to predict sudden death risk in patients with heart failure (HF). Heart failure affects more than five million Americans and increases therisk of sudden death. This application sets out to develop a simple, inexpensive blood test to help predict sudden death risk that may prevent un ...

    STTR Phase I 2012 Department of Health and Human Services
  10. Nanocytological Fecal Assessment to Personalize Colonoscopic Surveillance

    SBC: NANOCYTOMICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The clinical impact of the 5 million annual surveillance colonoscopies (follow up of previous neoplasia) is remarkably low (gt90% without significant neoplasia). Juxtaposed with this is the alarmingly frequent occurrence of colorectal cancers (CRCs) in between colonoscopies (interval cancers), especially in the proximal colon. The medico-legal and clinical ...

    STTR Phase I 2012 Department of Health and Human Services

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