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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Validation of a Negative Regulator as a Novel Therapy for Autoimmune Disease
SBC: Immunext, Inc. Topic: NIAIDDESCRIPTION (provided by applicant): The immune system depends upon an exquisite balance between positive and negative signals to maintain proper function. However, disruptions of this balance can lead to inappropriate responses: for example loss of negative regulation can result in autoimmunity. VISTA (V-region Immunoglobulin-containing Suppressor of T cell Activation), is a recently identified n ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
An Unobtrusive, Multi-individual Gait Monitor
SBC: RESPONSE APPLICATIONS, LLC Topic: NIADESCRIPTION (provided by applicant): We will develop an instrument to improve the healthcare of the most frail members of the elderly community. This population; elderly or recovering patients living at home or in an extended care facility is too frail toleave this environment and, as such, is subject to significantly reduced physical activity. Although numerous studies have confirmed that contin ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
A non-invasive high-throughput sleep stage analysis system
SBC: Pinnacle Technology, Inc. Topic: NIADESCRIPTION (provided by applicant): Degeneration of sleep quality with age is a well-documented phenomenon. While much is known regarding the characterization of this decline, remarkably little of the physiology or genetic underpinnings are understood. Age-related sleep changes in rodents (mice + rats) are remarkably similar to those seen in human populations and as such these animal models are f ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Electronic Location Reporting for Individuals With Alzheimers Disease and other D
SBC: INTELLISPEAK, LLC Topic: NIADESCRIPTION (provided by applicant): The proposed effort is aimed at the evaluation of a wireless electronic location system for reporting the location of individuals with Alzheimer's Disease and other Dementia (ADOD), who tend to wander or elope. This isa very vexing and routine problem for caregivers, and sometimes results in physical danger and emotional stress to the individuals who may ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Safe and effective anti CD154 antibodies for therapeutic intervention
SBC: IMMURX LLC Topic: NIAIDDESCRIPTION (provided by applicant): In both animal proof of concept studies and preliminary clinical trials, there is ample data demonstrating the potential therapeutic benefits o CD154 blockade for treatment of autoimmune diseases and organ transplantation. However, development of ?CD154 as a therapeutic has been impeded by antibody toxicity observed in early clinical trials. With nearly 50 mill ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
A Nicotine Biosensor for Addiction Studies
SBC: Pinnacle Technology, Inc. Topic: NIDADESCRIPTION (provided by applicant): Tobacco-related deaths cost the United States approximately 200 billion each year. Nicotine is singularly responsible for the dependence-forming properties of tobacco smoking and, once introduced to the body, rapidly affects the brain within 15 seconds. Breaking nicotine addiction is challenging and relapse rates remain high. The extremely rapid timescale of n ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Adherence Monitoring for Substance Abuse Clinical Trials
SBC: CREARE LLC Topic: NIDADESCRIPTION (provided by applicant): The evaluation and selection of safe and effective pharmacotherapies for drug abuse and addiction is performed through clinical trials that rely on patients taking the studied medication at the specified time and frequency. To ensure accurate efficacy measures, adherence to the prescribed regimen must be known. Creare proposes to develop an adherence monitoring ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Precision Particle Fabrication-enabled Betamethasone-loaded Microspheres for Tran
SBC: ORBIS BIOSCIENCES, INC. Topic: NIDCDDESCRIPTION (provided by applicant): Current approaches to treat sudden sensorineural hearing loss (SSNHL) do not maintain inner ear drug concentrations within an appropriate therapeutic window for sufficient lengths of time to achieve therapeutic effect.A novel delivery system for long-term, controlled release of glucocorticoid steroids to the inner ear would constitute a dramatic improvement in ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Cyano-Map: Linking cyanobacteria metrics and human health
SBC: APPLIED GEOSOLUTIONS LLC Topic: NIEHSDESCRIPTION (provided by applicant): Research at the intersection of limnology and public health is showing that toxins produced from cyanobacteria act as an environmental trigger for Amyotrophic Lateral Sclerosis (ALS) commonly known as Lou Gehrig's Disease. Additional linkages are being made between cyanobacteria and Parkinson's and several acute illnesses and neurological disorders. A ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health -
Engineering Microparticles for Taste-Masking and Controlled Release of Pediatric
SBC: ORBIS BIOSCIENCES, INC. Topic: NICHDDESCRIPTION (provided by applicant): Pediatric drug development presents many unique challenges in the effective treatment of diseases in children, from adequate dosing information and pediatric-specific testing to palatable flavor profiles and effective delivery formats. A novel technology that masks bitter drug flavors while providing flexibility in dose design and format would enable formulati ...
SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health