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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Locating the Elderly Overseen by Nurses- LEON

    SBC: Q-Track Corporation            Topic: NIA

    DESCRIPTION (provided by applicant): The proposed effort aims to develop a comprehensive wireless tracking and monitoring system for residents of Long Term Care facilities. The commercial product ElderAlertTM extends Q-Track's real-time location system totrack residents, caregivers, and medical assets within a LTC facility. ElderAlertTM directs caregivers to residents who have fallen or have ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  2. A NOVEL MICROFLUIDIC DEVICE FOR SELECTION AND OPTIMIZATION OF DRUG DELIVERY VEHIC

    SBC: CFD RESEARCH CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): We propose to develop and demonstrate a novel microfluidic device and assay for selection and optimization of delivery vehicles, specifically non-viral vectors for drug delivery to tumors. Tumor drug delivery is a complex phenomenon affected by several elements in addition to drug or delivery vehicle's physico-chemical properties. A key factor is tumor mic ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. New In Vitro Human Liver Toxicity Bioassay System

    SBC: Vivo Biosciences Inc            Topic: NIEHS

    DESCRIPTION (provided by applicant): The overall objective of this SBIR proposal is to develop and commercialize a human 3D or mini- liver bioassay system suitable for real-time analysis of metabolic functions and long-term drug toxicity profiles. At present, liver functions are mostly studied using HepG2 cell line and primary hepatocytes cultured onto collagen or polymer matrices. However, these ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. A novel physiologically realistic microfluidic in-vitro blood-brain barrier model

    SBC: CFD RESEARCH CORPORATION            Topic: NIGMS

    DESCRIPTION (provided by applicant): The overall objective of this study is to develop a novel in vitro microfluidic platform to test a drug or delivery vehicle's ability to permeate the Blood-Brain Barrier (BBB). In contrast to current in-vitro models, our proposed device, SIM-BBB, comprises of a microfluidic two-compartment chamber. The chamber is designed in such a way as to permit vis ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Electronic Location Reporting for Individuals With Cognitive Disabilities

    SBC: INTELLISPEAK, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The proposed effort is aimed at the development and evaluation of a wireless electronic location system for reporting the location of individuals with autism and other cognitive disabilities, who may wander or elope. This is a very vexing and routine problem for caregivers, and sometimes results in physical and emotional danger to the individuals who may wander ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Mitochondrial DNA repair agents for acute lung injury

    SBC: EXSCIEN CORPORATION            Topic: NHLBI

    DESCRIPTION (provided by applicant): Drug development for acute lung injury (ALI) has been marred by unfulfilled expectations. Perhaps best illustrating this unsatisfactory situation is the history of therapeutic strategies directed at inhibition of reactive oxygen species (ROS). While decades of laboratory and clinical studies make it clear that ROS are pathogenically important across the entire ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Delivery system development for a reservoir targeted Lyme disease vaccine

    SBC: FoodSource Lure Corporation            Topic: NIAID

    DESCRIPTION (provided by applicant): The incidence and geographic distribution of Lyme disease in the U.S. has increased steadily since its first description in 1977. Efforts to stem the spread of the disease through controlling the population of its tickvector and/or the mouse reservoirs of the disease have met with only limited success. The only approved human vaccine to protect against Lyme di ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Optimization of Protein Therapeutics Formulations

    SBC: SOLUBLE THERAPEUTICS, INC            Topic: NIGMS

    DESCRIPTION (provided by applicant): This proposal involves the development of a high-throughput self-interaction chromatography (SIC) system that will be used by Soluble Therapeutics, LLC, to improve and accelerate the formulation discovery process for biopharmaceuticals (i.e. vaccines, monoclonal antibodies and other therapeutic proteins). Biopharmaceuticals are used to treat a variety of infect ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Automated Delineation, Parcellation and Analysis of the Cerebellum from MR Images

    SBC: Neurobehavioral Research, Inc.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Cerebellar involvement has been implicated in a large spectrum of disorders. Reduced cerebellar volumes have been reported in alcoholism, autism spectrum disorders, schizophrenia, mood disorders, and essential head tremors. As an example of the work demonstrating the more widespread role of the cerebellum in brain function, Sullivan and colleagues have demonstr ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. A non-invasive high-throughput sleep stage analysis system

    SBC: Pinnacle Technology, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): Degeneration of sleep quality with age is a well-documented phenomenon. While much is known regarding the characterization of this decline, remarkably little of the physiology or genetic underpinnings are understood. Age-related sleep changes in rodents (mice + rats) are remarkably similar to those seen in human populations and as such these animal models are f ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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