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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Therapeutic factor XI blockade for sepsis

    SBC: Aronora, Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): This SBIR Phase II grant will support the commercial development of an injectable biological product candidate, a unique proprietary recombinant humanized anti-factor XI monoclonal antibody (AXIMAB), towards an investigational new drug (IND) application. The lead indication for AXIMAB is severe bacterial sepsis, which is a major cause of mortality in hospitaliz ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. Online Training for Resource Parents of Substance-Exposed Children

    SBC: NORTHWEST MEDIA, INC            Topic: NIDA

    DESCRIPTION (provided by applicant): While foster-adoptive parents receive some rudimentary training just prior to or in the early months following adoption finalization, many stil harbor unrealistic expectations about adoption and are unaware of the severe behavioral problems they may encounter, no less the role that exposure to substance abuse may play in the child's development. Our Phase ...

    SBIR Phase II 2012 Department of Health and Human Services

    SBC: Health Education Research Systems, llc            Topic: NIDA

    DESCRIPTION (provided by applicant): (Phase-2, Renewal) The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce community with the special focus on Substance-Addiction Disorders. SACC is an individual and group-level application platform th ...

    SBIR Phase II 2012 Department of Health and Human Services

    SBC: DAHL NATURAL L.L.C.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Development of a phase 2 beta for demonstration in Tree Top juice processing plant of a Field Applicable Real-time Remote Monitoring Sensor Device capable of detecting multiple pesticides simultaneously in unfiltered juice, fluid or waste water. We propose to further develop the carbon nanotube matrices active biosensor area for effective immobilization of mult ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Embosser Using Polymer Roller for Production of Improved Braille and Tactile Grap


    DESCRIPTION (provided by applicant): The specific aim of this proposal is to develop and implement a new type of technology for production of braille and tactile graphics that uses a system in which metal punch pins fire into a smooth polymer-coated shaftrather than into a machined metal die as with most current embossing technologies. The successful completion of this project will yield a new bra ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Electronic Location Reporting for Individuals With Cognitive Disabilities

    SBC: INTELLISPEAK, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The proposed effort is aimed at the development and evaluation of a wireless electronic location system for reporting the location of individuals with autism and other cognitive disabilities, who may wander or elope. This is a very vexing and routine problem for caregivers, and sometimes results in physical and emotional danger to the individuals who may wander ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Factor XI inhibitor for thrombosis

    SBC: Aronora, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Thrombotic cardiovascular diseases including venous thromboembolism (VTE), deep vein thrombosis (DVT), myocardial infarction, and ischemic stroke, remain leading causes of death and disability in the U.S. Although effective antithrombotic agents are available, these drugs inadvertently target vital hemostatic molecular mechanisms and can produce severe dose-lim ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Mission Reconnect: Promoting Resilience and Reintegration of Post-Deployment Vete

    SBC: Collinge And Associates, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): There is an urgent and growing need for mental health interventions supporting both short- and long-term reintegration of veterans of OIF and OEF into their communities and significant relationships. Innovative approaches are needed to support the well-being of veterans who may not access or be reached by formal services. Objectives. This Phase II project will ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. Integrated EEG/NIR Sensor System for Infants

    SBC: Electrical Geodesics, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): The goal of this SBIR project is to design a cost-effective, lightweight, integrated, whole-head dense-array electroencephalography and near-infrared spectroscopy (dEEG/NIRS) brain imaging and data analysis system for non-invasive recording of brain activity in neonates and young children. This system will permit bedside monitoring of immediate at-risk neonates ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Live-Cell Assays for Lysosomal Enzyme Activity


    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase II project aims to develop new targeted fluorogenic substrates capable of measuring lysosomal enzyme activity in living cells and tissues. If successful, the proposed research will provide breakthroughs needed to advance the discovery of promising new therapies and modulating drugs for lysosomal storage diseases and ...

    SBIR Phase II 2012 Department of Health and Human Services

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