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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Electronic Location Reporting for Individuals With Cognitive Disabilities

    SBC: INTELLISPEAK, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The proposed effort is aimed at the development and evaluation of a wireless electronic location system for reporting the location of individuals with autism and other cognitive disabilities, who may wander or elope. This is a very vexing and routine problem for caregivers, and sometimes results in physical and emotional danger to the individuals who may wander ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  2. A non-invasive high-throughput sleep stage analysis system

    SBC: Pinnacle Technology, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): Degeneration of sleep quality with age is a well-documented phenomenon. While much is known regarding the characterization of this decline, remarkably little of the physiology or genetic underpinnings are understood. Age-related sleep changes in rodents (mice + rats) are remarkably similar to those seen in human populations and as such these animal models are f ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Electronic Location Reporting for Individuals With Alzheimers Disease and other D

    SBC: INTELLISPEAK, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The proposed effort is aimed at the evaluation of a wireless electronic location system for reporting the location of individuals with Alzheimer's Disease and other Dementia (ADOD), who tend to wander or elope. This isa very vexing and routine problem for caregivers, and sometimes results in physical danger and emotional stress to the individuals who may ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. A Nicotine Biosensor for Addiction Studies

    SBC: Pinnacle Technology, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Tobacco-related deaths cost the United States approximately 200 billion each year. Nicotine is singularly responsible for the dependence-forming properties of tobacco smoking and, once introduced to the body, rapidly affects the brain within 15 seconds. Breaking nicotine addiction is challenging and relapse rates remain high. The extremely rapid timescale of n ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Precision Particle Fabrication-enabled Betamethasone-loaded Microspheres for Tran

    SBC: ORBIS BIOSCIENCES, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): Current approaches to treat sudden sensorineural hearing loss (SSNHL) do not maintain inner ear drug concentrations within an appropriate therapeutic window for sufficient lengths of time to achieve therapeutic effect.A novel delivery system for long-term, controlled release of glucocorticoid steroids to the inner ear would constitute a dramatic improvement in ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Engineering Microparticles for Taste-Masking and Controlled Release of Pediatric

    SBC: ORBIS BIOSCIENCES, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): Pediatric drug development presents many unique challenges in the effective treatment of diseases in children, from adequate dosing information and pediatric-specific testing to palatable flavor profiles and effective delivery formats. A novel technology that masks bitter drug flavors while providing flexibility in dose design and format would enable formulati ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. A Tissue Implantable Microbiosensor

    SBC: Pinnacle Technology, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): The aim of this application is to develop, prototype, validate, manufacture and commercialize a new, generalized microbiosensor designed for non-human use and based on functionalized nanoparticles. The microbiosensors produced will enable in vivo monitoring of a wide range of non-electroactive, neurologically relevant analytes, including, but not limited to, gl ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Ultra-low-power analog seizure detection algorithm

    SBC: FLINT HILLS SCIENTIFIC, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Development of implantable devices for automated detection, quantification, warning and delivery of therapy to block seizures is a very important unmet medical need. Making such a device as small as possible, minimizin g replacement surgeries, and maximizing device longevity and/or time between battery recharging are some of the most important development driv ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. From Nanoparticles to Novel Protective Garments

    SBC: NanoScale Materials, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop breathable, lightweight and disposable chemical protective clothing for use by personnel associated with law enforcement agencies, emergency medical services, medical/triage facili ties, and other federal, state, or local emergency agencies as well as by fire fighters and civilian first responders. This goal will be accomp ...

    SBIR Phase II 2008 Department of Health and Human ServicesCenters for Disease Control and Prevention
  10. SBIR TOPIC 252- FUNCTIONALIZED BIMAGNETIC CORE/SHELL FE/FE3O4 STEALTH NANOPARTIC

    SBC: NanoScale Materials, Inc.            Topic: N/A

    Early diagnosis and early treatment of cancer greatly improve the likelihood of long-term survival and health. Chemical structures that are selectively taken by cancerous tissue can be used to pull diagnostic and therapeutic moieties to cancerous tissue. Appropriately sized iron and/or iron oxide nanoparticles are effective for both diagnosis (via magnetic resonance imaging, MRI) and therapy (by h ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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