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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Oral delivered bone building therapy for osteoporosis

    SBC: OsteoGeneX Inc            Topic: NIAMS

    DESCRIPTION (provided by applicant): The osteoporosis market is still in demand for new therapeutics due to the lack of safe orally available bone building drugs. Currently, parathyroid hormone (PTH; FORTEOTM) and its analogs are the only bone building therapies available yet they capture only 8% of the osteoporosis market due to significant dosing and safety limitations. OsteoGeneX is developing ...

    SBIR Phase I 2013 Department of Health and Human Services
  2. Group housing: A robotic system to track and interact with individuals

    SBC: Pinnacle Technology, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): Individually housing animals, even for a short period, is known to have a negative influence on behavior, learning ability, and physiology. Group-housed rodents are better able to cope with stress through improved behavioral and physiological responses. Unfortunately, many experiments, including those designed to measure behavior, circadian activity, and/or sle ...

    SBIR Phase I 2013 Department of Health and Human Services
  3. Simplifying fMRI Integration in the Cognitive Neurosciences

    SBC: Perception Research Systems Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): Over the last two decades, fMRI has evolved into a widely used technology in basic biobehavioral research. The user base for this technology continues to increase due to the growth of the field of cognitive neuroscience, and this increase is poised to accelerate with adoption of fMRI to large-scale multi-site studies, translational studies, and clinical trials. ...

    SBIR Phase I 2013 Department of Health and Human Services
  4. Enabling Mobile Device-Based Stimulus Presentation in Biobehavioral Research

    SBC: Perception Research Systems Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): The ubiquity of high-performance mobile devices, such as smartphones and tablets, has the potential to significantly broaden and improve the methods of data collection used in the biobehavioral sciences. Contemporary mobile devices are capable of highly engaging and millisecond accurate stimulus presentation, reaction time measurements, and remote data retrieva ...

    SBIR Phase I 2013 Department of Health and Human Services
  5. A Nicotine Biosensor for Addiction Studies

    SBC: Pinnacle Technology, Inc.            Topic: NIDA

    ABSTRACT Tobacco-related deaths cost the United States approximately 200 billion each year. Nicotine is singularly responsible for the dependence-forming properties of tobacco smoking and, once introduced to the body, affects the brain within 15 seconds.Breaking nicotine addiction is challenging and relapse rates remain high. The extremely rapid timescale of nicotine action renders existing techn ...

    SBIR Phase II 2013 Department of Health and Human Services
  6. Expanding Precision Particle Fabrication Technology for the Widespread Control of

    SBC: ORBIS BIOSCIENCES, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant A critical need currently exists in the pharmaceutical market for microparticles that can accurately and effectively control the release of poorly water soluble compounds Although these poorly water soluble drugs are projected to have high clinical efficacy they are often rejected in the early stages of research because of the high cost and technical difficulties ...

    SBIR Phase II 2013 Department of Health and Human Services
  7. Electronic Location Reporting for Individuals With Cognitive Disabilities

    SBC: INTELLISPEAK, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The proposed effort is aimed at the development and evaluation of a wireless electronic location system for reporting the location of individuals with autism and other cognitive disabilities, who may wander or elope. This is a very vexing and routine problem for caregivers, and sometimes results in physical and emotional danger to the individuals who may wander ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. A non-invasive high-throughput sleep stage analysis system

    SBC: Pinnacle Technology, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): Degeneration of sleep quality with age is a well-documented phenomenon. While much is known regarding the characterization of this decline, remarkably little of the physiology or genetic underpinnings are understood. Age-related sleep changes in rodents (mice + rats) are remarkably similar to those seen in human populations and as such these animal models are f ...

    SBIR Phase I 2012 Department of Health and Human Services
  9. Electronic Location Reporting for Individuals With Alzheimers Disease and other D

    SBC: INTELLISPEAK, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): The proposed effort is aimed at the evaluation of a wireless electronic location system for reporting the location of individuals with Alzheimer's Disease and other Dementia (ADOD), who tend to wander or elope. This isa very vexing and routine problem for caregivers, and sometimes results in physical danger and emotional stress to the individuals who may ...

    SBIR Phase I 2012 Department of Health and Human Services
  10. A Nicotine Biosensor for Addiction Studies

    SBC: Pinnacle Technology, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Tobacco-related deaths cost the United States approximately 200 billion each year. Nicotine is singularly responsible for the dependence-forming properties of tobacco smoking and, once introduced to the body, rapidly affects the brain within 15 seconds. Breaking nicotine addiction is challenging and relapse rates remain high. The extremely rapid timescale of n ...

    SBIR Phase I 2012 Department of Health and Human Services

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