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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Responsible Retailing Program for Alcohol Retailers

    SBC: RRF FIELD SERVICES, LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): The Responsible Retailing Forum ( RRF ) has developed a new model to reduce sales of alcohol products to minors. Derived from recommendations contained in the Report on Best Practices for Responsible Retailing, prepared as a federal guidance document for the Center for Substance Abuse Prevention in 2002, the model employs a quality improvement approach to ass ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. Life Is A Stage: Dementia Care and the Dramatic Arts

    SBC: HEARTHSTONE ALZHEIMER CARE, LTD            Topic: NIA

    DESCRIPTION (provided by applicant): Market potential exists for development of works of drama that can be performed in facilities providing care for persons with dementia, and which can involve such residents interactively. Therefore, the purpose of thisPhase 2 project is to refine two plays created in our Phase 1 SBIR (Life Is A Stage : Dementia Care and the Dramatic Arts) that can be performed ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. The Hearthside Book Club: Pioneering Dementia-Level-Appropriate Reading Materials

    SBC: HEARTHSTONE ALZHEIMER CARE, LTD            Topic: NIA

    DESCRIPTION (provided by applicant): An estimated 5.4 million Americans are currently suffering from Alzheimer's disease (AD), and AD cases are expected to rise at an alarming rate, so market potential exists for products, approaches, and/or training thatcan help treat and/or circumvent the challenging behaviors associated with the condition. One approach that has been shown to be effective i ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Identification of Novel Broad Spectrum Influenza Virus Inhibitors

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Our goal is to develop small molecule inhibitors that target influenza entry. In Phase I, we identified several compounds that selectively inhibit the hemagglutinin (HA) mediated virus entry process. Three HA specific entry inhibitors (MBX494, MBX994, and MBX726) were selected for further research and development based on their antiviral potency, selectivity an ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Novel Methylenecyclopropane Analogues as Anti-Human Herpesvirus 6 and 8 Agents

    SBC: MICROBIOTIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The human herpesviridae family contains eight members divided into three subfamilies, designated alpha, beta and gamma. The alpha herpes viruses include herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) and varicella zoster virus (VZV). The beta herpes viruses include human cytomegalovirus (HCMV), two variants of human herpes virus 6 (HHV ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. A Rapid Point-of-care Diagnostic for C. trachomatis STDs

    SBC: NetBio, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Improved diagnosis of Chlamydia trachomatis (Ct) infections represents a critical unmet medical need. Ct is the most common cause of bacterial sexually transmitted diseases (STD) worldwide, and the Centers for Disease Control and Prevention estimate that there are 2.8 million US cases annually. Currently, 40% of women with untreated infection will develop pelvi ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Low-Cost Digital Gene Expression System

    SBC: INTELLIGENT BIO-SYSTEMS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): As the second most common cause of death in the US, cancer is caused by random mutations in an organism's genome. Although precise knowledge of the genomic sequence within neoplastic tissues can be an indicator for treatment, for example the erbB-2 receptor gene (Her-2) for breast cancer, such correlations are few and often do not adequately define tumor s ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. Proteome Bead-Display for Discovery of Tumor Antigens

    SBC: AMBERGEN, INC            Topic: NCI

    DESCRIPTION (provided by applicant): There is an urgent need for early-detection cancer biomarkers which can significantly lower the high mortality and cost of treating cancer. One of the most promising candidates for such biomarkers is tumor-associated autoantigens (TAA), autoantibodies to which have been detected in patient's blood even in the early stages of cancer. In addition to use in e ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. A kit based PET agent: edotreotide Ga 68 for clinical imaging of somatostatin rec

    SBC: MOLECULAR INSIGHT PHARMACEUTICALS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): A kit based PET agent: edotreotide Ga 68 for clinical imaging of somatostatin receptor expressing tissue. Synthetic peptides targeted to Somatostatin receptors (SSTR) were developed almost 30 years ago by Novartis to inhibit the effects of endogenous growth factors on malignant tissues. The radio-therapeutic version has been licensed to Molecular Insight (MIP) ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. Innovative Speech Articulation Tools for Neuroscience Research

    SBC: SPEECH TECHNOLOGY/APPLIED RESEARCH CORP.            Topic: NIDCD

    DESCRIPTION (provided by applicant): Changes in speech articulation can accompany many biomedical disorders and conditions that affect neurological control of speech. Historically, measuring these changes by acoustic analysis has required either laborioushand measurement or computer programming skill. As part of the output of previous work, we have developed fast automatic computer procedures base ...

    SBIR Phase II 2012 Department of Health and Human Services

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