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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. New High Performance Water Vapor Membranes To Improve Fuel Cell Balance of Plant Efficiency and Lower Costs

    SBC: TETRAMER TECHNOLOGIES LLC            Topic: 03b

    This project targets improved efficiency and lower cost of proton exchange membrane fuel cells through the development of improved water vapor management. Fuel cells are highly efficient, non-polluting source of energy that can significantly decrease the US dependence on foreign oil while reducing carbon dioxide emissions. Further improvements in performance and lower cost are needed to greatly ex ...

    SBIR Phase II 2012 Department of Energy
  2. Development and Commercialization of Nanocomposite Coating Technologies

    SBC: TETRAMER TECHNOLOGIES LLC            Topic: 02b

    There is a Global Safeguards need for tamper-indicating coatings of varying complexity for use in the verification and authentication of nuclear security documents, materials, and equipment. Current commercial coatings for seals used in this type of application lack the sophistication necessary for quick, accurate, and reliable tamper detection. In addition to tampering, another vital attribute is ...

    SBIR Phase I 2012 Department of Energy
  3. Targeting RNA conformation for drug development

    SBC: NUBAD LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for AIDS. Targeting specific RNA- protein interactions, such as Tat-TAR or Rev-RRE, which are involved in proliferation and survival of HIV-1 is a pro ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Online Training Support System for Community-Based Substance Abuse Agencies

    SBC: Sheidow Consulting, Inc.            Topic: NIDA

    DESCRIPTION (provided by applicant): Drug abusing and dependent youth represent a greatly under-served population at high risk of presenting significant deleterious long-term outcomes for themselves, their families, communities and society at extraordinary long-term costs. Adolescent substance use has been linked to serious problems including automobile accidents, increased rates of risky sexual ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Non-Enzymatic Cryogenic Isolation of Therapeutic Cells

    SBC: Cell & Tissue Systems, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): In modern day medicine, cellular therapies, regenerative medicine and tissue engineering all involve technologies for harvesting, expanding, modifying and re-implanting live viable cells and tissues. Processes for preparing the therapeutic products that incorporate living cells are critical for the stability and potency of th products but may be inherently inju ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Feasibility of immunotherapy by ice-free cryopreservation of engineered human all

    SBC: Cell & Tissue Systems, Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Autologous regenerative medicine tissue therapy costs are very high because when individual tissues are manufactured all the costs fall on a single patient. Allogeneic tissues are cheaper because large tissue batches can be made and the costs are shared by many patients. Allogeneic tissues are commonly treated to remove cell-associated antigens by decellulariza ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a novel connexin-based peptide for the treatment of corneal injury

    SBC: FirstString Research, Inc            Topic: NEI

    DESCRIPTION (provided by applicant): According to the World Health Organization, at least 171 million people worldwide are living with diabetes and this figure is likely to more than double by the year 2030. Because of its chronic nature, the severity of its complications and the means required to control them, the economic burden is enormous not only to the individuals and families involved but a ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Neuroprotective agents for retinal diseases

    SBC: Mitochem Therapeutics, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): Retinal degeneration can be triggered by environmental insults as well as genetic mutations. The role for most disease genes is unclear and pathological processes are influenced environment making it difficult to identify one central cause. Indeed, the genetics of age-related macular degeneration (AMD) and other forms of retinal degeneration point to multip ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. A sample stabilization system for HIV in Plasma and Whole Blood

    SBC: ACXEND            Topic: NHLBI

    DESCRIPTION (provided by applicant): Nucleic acid analysis is the essential foundation of many biomedical research and diagnostic methods. Quantitative molecular diagnostic methods are critically dependent on the ability to stabilize the collected sampleprior to purification and analysis. While conventional methods for invasive blood draw procedures exist, there is a desire and movement in both ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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