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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Point of Care Detection of Respiratory Viruses
SBC: LUCIGEN CORPORATION Topic: NIAIDDESCRIPTION (provided by applicant): Respiratory infections have a significant health and economic impact worldwide. Current test products for the diagnosis of respiratory viral infections such as influenza are inadequate for the timely diagnosis needed for successful implementation of antiviral treatment. Unfortunately a test product that can accurately diagnose common respiratory viruses with hi ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Random Shear Shuttle BAC Libraries for Antimicrobial Discovery from Soil Metageno
SBC: LUCIGEN CORPORATION Topic: NIAIDDESCRIPTION (provided by applicant): 100,000 Americans perish each year due to untreatable bacterial infections. The societal benefits of new antibiotic compounds that are effective against numerous multiple drug resistant pathogens would be significant. The best possible source for new antibiotic structures with potentially novel mechanisms of action is within natural environments, particularly s ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Engineered tissue-based, high-throughput compound profiling
SBC: Invivosciences, Inc. Topic: NIGMSDESCRIPTION (provided by applicant): Current NIGMS-SBIR funding supported InvivoSciences LLC's (IVS) launch of several product lines in 2010. IVS generated revenues from the sales of three-dimensional (3D) cell culture tools (MC-8TM and IVS InsertsTM) thatcan grow various hydrogel tissues without any support layers. The culture tools enable Palpator TM and Tissue StretcherTM to stretch the hy ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
NOVEL SOLUBILITY-ENHANCING PROTEIN EXPRESSION TECHNOLOGY
SBC: LUCIGEN CORPORATION Topic: NIGMSDESCRIPTION (provided by applicant): A major goal in the post-genomic era is to express the vast collection of protein- coding sequences, eventually resulting in a better understanding of protein interactions and the development of novel therapeutics. Themost favored host for heterologous recombinant protein expression is Escherichia coli. Despite many improvements, producing soluble proteins in E ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Intelligent Prosthetic Socket with Variable Volume and Elevated Vacuum Systems
SBC: SMART SURFACE DESIGNS, LLC Topic: NICHDDESCRIPTION (provided by applicant): Patient socket performance is a critical barrier to progress in rehabilitation, the most common source of patient dissatisfaction and part of a growing medical and socioeconomic problem. Poor socket performance is a greatly uncharacterized multi-factorial problem that leads to skin degeneration and patient discomfort (~75% of all patients). This proposal has a ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Screening Device for Differentiated Primary Cell Models of Airway Epithelia
SBC: Bellbrook Labs, LLC Topic: NHLBIDESCRIPTION (provided by applicant): Approaches to drug screening typically involve dramatic compromises in order to achieve high throughput and hold down costs. Examples include the use of immortalized, heterologous cell lines, and genetic engineering toover-express the target protein and/or incorporate a fluorescent surrogate reporter to display the result. At least partly because such systems o ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Targeting System Xc- for the Treatment of Schizophrenia
SBC: Promentis Pharmaceuticals Topic: NIMHDESCRIPTION (provided by applicant): Schizophrenia is a chronic and debilitating disorder that impacts nearly 1% of the world's population. The burden on the families and caregivers of patients is immense, with the cost of care in the United States being greater than 60 billion annually. The exorbitant financial strain of schizophrenia arises, in large part, to a lack of innovation that has ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Automated Interactive Text Messaging to Assess Adolescent Depression
SBC: KOBAK, KENNETH A Topic: NIMHDESCRIPTION (provided by applicant): The internet is an increasingly important resource for clinicians to access training materials and resources for treatment delivery of evidence-based treatments such as cognitive behavioral therapy (CBT) and antidepressant medications. This project proposes to develop a secure, web-based resource to provide therapists with instructional materials for scheduling ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Modeling Professional Attitudes and Teaching Humanistic Communication in VR
SBC: MEDICAL CYBERWORLDS, INC. Topic: NCATSDESCRIPTION (provided by applicant): Modeling Professional Attitudes and Teaching Humanistic Communication in VR (MPathic-VR) Patients with life-threatening cancer need caregivers who can help them through difficult decisions by understanding their interests, values, and beliefs, and who communicate empathically with the patient's family and friends, and effectively with their medical peer ...
SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health -
Speech-based biomarkers of CNS dysfunction associated with early Alzheimers disea
SBC: KOBAK, KENNETH A Topic: NIADESCRIPTION (provided by applicant): More efficient methods to screen and monitor elderly patients in clinical practice and research are needed, but visits to clinical offices are expensive and many older patient are restricted by mobility or transportation access. The Alzheimer's Disease Cooperative Study (ADCS) is evaluating several technology platforms for remotely monitoring patient stat ...
STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health