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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Nezavist a Novel Molecule for Treatment of Alcohol Use Disorder
SBC: LOHOCLA RESEARCH CORPORATION Topic: 150Abstract for Supplement ApplicationThe ultimate goal for our original project was to complete the proof-of-concept work, and the multitude of pharmacodynamic, pharmacokinetic, toxicokinetic, safety, and toxicology studies required by the FDA to apply for an IND. We are fully satisfied that we have generated a new chemical entity that acts at a novel binding site on the GABA-A receptor and acts in ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
TOPIC 363: myCare2- Supporting Caregivers and Caregiving
SBC: BRIGHTOUTCOME INC. Topic: NCIThe myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Nonsense Suppressing Drugs for Rett Syndrome
SBC: Starwise Therapeutics LLC Topic: 103Nonsense Suppressing Drugs for Rett Syndrome Rett syndromeRTTis a devastating genetic condition that affects mostly femalesIt is one of the worst types of neurodevelopmental disordersthe affected girls are born without any obvious problemsdevelop in a seemingly typical manner for the first year of lifebut then abruptly and without warning lose most of their acquired abilitiesRTT girls then typical ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Integrated System for Rapid Production of Activated Sugars and Glycosylated Molecules
SBC: ZUCHEM INC. Topic: 300Glycan modifications of natural products are increasingly important in the discovery of new pharmaceuticalsWhile glycodiversity gives rise to important therapeutic properties of bioactive moleculesexploring glycodiversity has challengesIsolating glycosylated compounds from nature is often difficult due to low concentrations and the presence of multiple related molecules with similar structures and ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Middle-ear reflex testing using WAI
SBC: Mimosa Acoustics Inc. Topic: NIDCDPROJECT SUMMARYThe purpose of the proposed project is to combine wideband acoustic immittanceWAIand middle ear muscle reflexMEMRtesting using new approaches that improve sensitivityincrease test efficiencyand provide objectivity in interpretationAcoustically elicited MEMRs have a long history of value in the clinical evaluation of hearing lossWhile sensitive to and affected by middle ear disorders ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Clinical optical coherence tomography for retinal metabolic imaging
SBC: OPTICENT, INC. Topic: NEIPROJECT SUMMARY Diabetic retinopathyDRis a complication of diabetes and a leading cause of blindness in the worldAlthough it is widely accepted that DR is driven by ischemiathe current grading of DR severity is based only on structural alterations such as the presence of abnormal retinal microvasculature in non proliferative DR or angiogenesis in proliferative DRAs a resultmost patients have alrea ...
SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
A Sensor-based Platform for Hand Hygiene Tracking and Analysis
SBC: Microsensor Labs, LLC Topic: 600Project Summary This Small Business Innovation Research Phaseproject aims to develop and characterize a sensor based platform to track and analyze healthcare providershand hygiene quality and compliance automatically and continuouslyHealthcare Associated InfectionsHAIsare the most common type of complication for patients who are hospitalizedIn the United Statesout of everyhospitalized patients is ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
The first cell-based and label-free, high-throughput assay of specific enzyme activities
SBC: SAMDI TECH, INC. Topic: 950Project SummaryAbstract Cell based assays that investigate the effect of small molecules on cellular activities are becoming increasingly popular screening tools for drug discoveryThe ability to assess small molecules in a physiologically relevant environment is informativeas the assays simultaneously evaluate compound permeabilitytoxicityand activityYetcell based assays are often limited to detec ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A novel glutaminase-free mammalian asparaginase with minimized immunogenicity to enable expanded use in cancer therapy
SBC: Enzyme by Design Inc. Topic: 102PROJECT SUMMARY Enzyme by DesignIncEbDis developing a safer version of L asparaginase that can be used routinely in the treatment of adult ALL patients whose hypersensitivity to todayandapos s bacterial L asparaginases deprives them from this efficacious therapyEbDandapos s L asparaginase is novel due to its mammalianguinea pigorigin and its lack of L glutaminase co activityThe need for better the ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Point-of-Care Wearable Pressure and Temperature Sensor System for Therapeutic Compression Garments and Venous Leg Ulcers
SBC: WEARIFI, INC. Topic: NIAPROJECT SUMMARYVenous leg ulcersVLUsare the most common ulcerative wounds in the elderly affectingof all individuals older thanMore thanelderly individuals suffer from VLUswhich cost nearly $USDs to treat a single ulcerThe overall cost to the medical system is $billion USDs yearlyAlthough there have been significant advances in the science of wound care including the development of novel bioengine ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health