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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Confocal and Autofluorescence Imaging of Macular Degeneration using a Low Cost Digital Imager

    SBC: AEON IMAGING LLC            Topic: NEI

    Project SummaryAbstract The overall goal of the proposed SBIR Phase II research is to build and evaluate a low costmulti mode retinal camera used to detect and manage causes of macular impairmentAge related macular degenerationAMDremains the most common cause of permanent vision loss in the US and many industrialized countriesTreatments with portable lasers and injectable drugs can save sightbut e ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Polymeric nanoparticles for inductive browning of white adipose tissue

    SBC: ADIPO THERAPEUTICS, LLC            Topic: 200

    Global epidemics of obesity and its associated comorbidities pose formidable challenges to human healthCurrent few medications available for obesity treatment only produce modest effects and are usually accompanied with unpleasantpotentially harmful side effectsThere is accumulating evidence that significant metabolic differences that distinguish beige brown adipocytes from white adipocytes can po ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein-protein interaction

    SBC: ANAGIN            Topic: 103

    Abstract This application, “Development of novel small molecule analgesics modulating the nNOS-NOS1AP protein- protein interaction,” addresses the critical need for more effective medications to treat chronic neuropathic pain affecting ~116 million people in the United States. Current pain medications such as NSAIDS, steroids, opiates and gabapentin analogs have documented and often severe sid ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development and feasibility of prevention-minded oral health mobile App based on dietary selections and oral hygiene events.

    SBC: Indiana Nanotech, LLC            Topic: NIDCR

    The number of decayed and filled tooth surfaces in primary dentition is on the rise in US children between the ages ofandyears oldin factof adolescentsbetweenandyears oldandout ofdentate seniorsagebear evidence of dental cariesReinforced with areport statingof those between the ages ofandhave dental cariesvirtually all walks of life are thus affectedand this doesn t even include those unreportedor ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Fluoroscopic drill attachment for orthopedic trauma surgery

    SBC: ECLIPSE ORTHOPAEDICS, LLC            Topic: NIAMS

    Abstract Aboutleg and hip fractures each year are treated by implanting a stiff metal rod or intramedullaryIMnailthrough the center of the bone and fixing the ends of the nail to the bone with screwsBut placing the locking screws to fix the rod to the bone is difficultTo anchor the nail securelythe surgeon must accurately drill pilot holes through both the bone and locking holes in the nailwhile t ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Software and services to advance dose-response modeling in chemical risk assesment

    SBC: KS & ASSOCIATES LLC            Topic: NCATS

    PROJECT SUMMARY Chemical risk assessment has been widely applied in chemical industry as a necessary step to get new commercial chemicals registeredand in governmental agencies as a critical procedure to evaluate the toxicity of chemicals in order to properly regulate them to protect human health and the environmentThe Lautenberg Chemical Safety Act further strengthens the importance of chemical r ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Targeting Therapeutics for Accelerated Bone Fracture Repair

    SBC: Novosteo Inc.            Topic: NIDCR

    Project Summary Abstract SignificanceThe failure of bone fractures to adequately repair in elderly patients causes significant morbidity and mortality each year in the United StatesThis problem will continue to be exacerbated by an aging populationwith aincrease in hip fractures alone expected byand significant costs in lost workquality of lifephysical therapyextended care facility staysand surger ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Development of fully integrated electrochemical device for detecting metals in biological fluids

    SBC: Bioanalytical Systems, Inc.            Topic: NIEHS

    Exposure to toxic levels of metals causes significant negative chronic health problems in the exposed populationsDuring and after exposuremetals such as manganeseleadnickelmercuryetcare present in biological fluidsA fully integrated wearable device would enable real time monitoring of exposure levelsThis would quickly alert those exposed to toxic concentrations of metals and mitigate the chronic h ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. HealthLink: A blockchain-enabled healthcare network for population health data

    SBC: CONSENSUS NETWORKS INC.            Topic: NLM

    Abstract Summary This project seeks to bring population health data to the blockchainBlockchain technology gives health data the opportunity for an immutable data trail for auditing and billing purposesenhanced security and encryption leading to better patient privacy and enabling more widespread longitudinal patient trackingand distribution of data which will minimize cyber threats to health syst ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Optimization of small molecule SERCA2b activators to inhibit neuron loss in Alzheimer's disease

    SBC: NEURODON, LLC            Topic: NIA

    Alzheimer s diseaseADis an immense national public health burdenIt is theth leading cause of death in the US with overmillion Americans sufferingand costs of over $billion in health care and related expensesThis patient population is expected to almost triple over the nextyearsDespite this urgent needthere are currently no disease modifying agents approvedNeuron loss is the only physiological phen ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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