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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Decentralized, Public, and Mobile-Based Sidewalk Inventory Tool (MySidewalk)

    SBC: KNOWLEDGE BASED SYSTEMS, INC.            Topic: 142FH1

    Knowledge Based Systems, Inc. (KBSI) is pleased to propose the further design and development of MySidewalk™ mobile application facilitating the crowd-sourced collection of sidewalk inventory and condition data. The MySidewalk™ application utilized advances in social networks and data mining to provide integrated sidewalk datasets. Phase I and II research was facilitated by inputs from City ...

    SBIR Phase II 2019 Department of Transportation
  2. Extended Release of Pyridostigmine Bromide for Effectively Combating Nerve Agent Exposure

    SBC: Innosense Llc            Topic: CBD181004

    Chemical warfare agents such as the lethal nerve agent soman are a major source of risk to military personnel. Currently, pyridostigminebromide (PB) is the only FDA-approved pretreatment to counteract the effects of soman. The rationale behind PB administration is that it actsas a temporary inhibitor of AChE. This precludes nerve agents from irreversible inactivation of AChE, thereby mitigating th ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  3. Biphase Extended Release Tablet Formulation for Nerve Agent Pretreatment

    SBC: Zymeron Corporation            Topic: CBD181004

    Given the unforeseen/unanticipated use of nerve agents in the battlefield and on the homeland, military personnel can benefit from this oncedaily pretreatment. It may also be desirable to pretreat certain medical and emergency aid personnel following a known/suspected nerveagent attack. Also, a novel, improved PB extended release formulations can be commercialized for the treatment of myasthenia g ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  4. Stable Formulation of Nerve Agent Intoxication Countermeasures

    SBC: Luna Innovations Incorporated            Topic: CBD181005

    In response to the defined need for minimizing the carry weight of combat teams while retaining capability, Luna Innovations is proposing thedevelopment of a stable formulation of atropine and scopolamine for use in an autoinjector to combat nerve agent intoxication. Thecombined formulation of atropine and scopolamine will allow for better treatment with more physiological coverage within the huma ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  5. Dual Formulation of Atropine and Scopolamine with Enhanced Stability

    SBC: Nano Terra, Inc.            Topic: CBD181005

    The standard US military treatment for nerve agent exposure is application of up to three autoinjectors, each containing atropine sulfate and2-pralidoxime, to counteract symptoms of nerve agent intoxication and restore acetylcholinesterase activity. This treatment increases survivalrates after nerve agent exposure, however, seizures resulting from nerve agent poisoning are a common symptom that ca ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  6. Dual Formulation of Atropine/Scopolamine with Enhanced Stability

    SBC: Cmc Pharmaceuticals, Inc.            Topic: CBD181005

    CMC Pharmaceuticals, Inc. (Cleveland, OH) is proposing developing a stable, combination product of two small molecule drug candidates as acounter measure to chemical warfare nerve agents (NA). The combination product is expected to exploit complementary pharmacologicalprofiles for optimal muscarinic receptor blockade and anticholinergic activity within the peripheral and central nervous system. It ...

    SBIR Phase I 2019 Department of DefenseOffice for Chemical and Biological Defense
  7. Tomographic Nanoscopy for Pathogen Identification

    SBC: SOLID STATE SCIENTIFIC CORPORATION            Topic: CBD171003

    This effort will augment the capabilities of an existing all reflecting, confocal FTIR microscope to allow for digital holographic imaging as wellspectral content determination at video frame rates. The use of a dual beam frequency comb, with a beam path coincident with the pathrequired for the digital holographic imaging, will allow spectral determination of any organism being holographically ima ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  8. Process Development and Manufacture of an Antibody-based Therapy Against Sudan EbolaVirus

    SBC: BIOFACTURA, INC.            Topic: CBD171005

    Recently we have observed a massive outbreak of Ebola virus. This family of virus causes a significant bioterrorism threat due to the high levelof mortality, rate of transmissibility and the lack of an approved vaccine or therapy directed against it. The goal of this proposal is to develop,optimize and scale-up a mammalian cell culture-based bioprocess for the rapid manufacture of an antibody-base ...

    SBIR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  9. Collaboration-Optimized Network for Naturlistic Exploration and Communication about Traffic (CONNECT)

    SBC: APTIMA, INC.            Topic: 081NH2

    Collaboration-Optimized Network for Naturalistic Exploration and Communication about Traffic (CONNECT) 3/19/2018 Collaboration-Optimized Network for Naturalistic Exploration and Communication about Traffic (CONNECT) will be a tool that allows users to easily generate a wide range of data visualizations from the Fatality Analysis Reporting System (FARS). CONNECT will leverage open-source visual ...

    SBIR Phase I 2018 Department of Transportation
  10. High-Spatial and Hyperspectral-Resolution Imaging for Bridge Inspection

    SBC: Aware Vehicles, Inc.            Topic: 180FH2

    High-Spatial and Hyperspectral-Resolution Imaging for Bridge Inspection 3/12/2018 Four out of 10 national bridges have been in service for 50 or more years which have undergone different levels of structural deficiency; other relatively newer bridges are constantly exposed to natural and artificial hazards and are likely structurally deficient in their life cycles. This SBIR project aims to de ...

    SBIR Phase I 2018 Department of Transportation

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