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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. IMPROVED AEROSOL CAN

    SBC: Materials Engineering &            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Transportation
  2. Pediatric Acceptable Formulation of Amiodarone

    SBC: ACADEMIC PHARMACEUTICALS INC            Topic: N/A

    DESCRIPTION (provided by applicant): IV amiodarone is the first line therapy for life threatening ventricular as well as supraventricular arrhythmias. However, the Tween 80 and benzyl alcohol diluents limits the rate of administration severely, due to hypotension and myocardial contractile depression. These adverse toxicities contribute to the high mortality of cardiac arrest patients who have ma ...

    SBIR Phase I 2009 Department of Health and Human Services
  3. Controlled Release Vascular Grafts

    SBC: VesselTek Biomedical LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In the United States, it is estimated that 8 million people suffer from peripheral artery disease (PAD). PAD is characterized by a gradual reduction in blood flow to the muscular arteries of the lower extremities caused by atherosclerosis. For those with severe PAD, lower extremity bypass grafting remains the predominant option for limb salvage. Although native ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. Non-invasive Assessment of Insulin Resistance

    SBC: BIOCHEMANALYSIS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of this grant is to develop a non-invasive method for assessment of insulin resistance and impaired glucose tolerance (IGT) as a measure of pre-diabetes suitable for application to large-scale screening studies and to individualized preventive strategies in patients at risk for development of diabetes. This new approach is based on the kno ...

    SBIR Phase II 2009 Department of Health and Human Services
  5. MULTIDIRECTIONAL ULTRASONIC BLOOD-FLOW-IMAGING SYSTEM

    SBC: BIO-IMAGING RESEARCH, INC.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  6. MICROHOLOGRAPHIC DIAGNOSIS OF CERVICAL NEOPLASIA

    SBC: BIO-LOGIC SYSTEMS CORPORATION            Topic: N/A

    THIS RESEARCH WILL DEVELOP A MICROHOLOGRAPHIC TECHNIQUE FOR THE DIAGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN). THE DESIGN OF THE INSTRUMENT WILL ALLOW FOR THE RECORDING OF THE FEMALE GENITAL TRACT, IN PARTICULAR THE CERVIX, WHICH CAN BE SUBSEQUENTLY EXAMINED UNDER A MICROSCOPE WITH RESOLUTION COMPARABLE TO THAT OBTAINED IN PATHOLOGICAL AND HISTOLOGICAL EXAMINATIONS. THE METHOD UTILIZES CON ...

    SBIR Phase I 1990 Department of Health and Human Services
  7. Development of novel tissue directed ultra sound therapeutic gene delivery system

    SBC: SONOGENE, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Low levels of high-density lipoprotein (HDL) cholesterol is an important risk factor for coronary heart disease (CHD). HDL cholesterol levels are predictive of major cardiovascular events in patients treated with statins. This relationship was also observed among patients with LDL cholesterol levels below 70 mg per deciliter. Studies have demonstrated that poly ...

    SBIR Phase I 2009 Department of Health and Human Services
  8. MORPHOMETRIC SOFTWARE FOR CRANIOFACIAL ASSESSMENT

    SBC: Coe-truman Technologies            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  9. Instrument for assessment of pediatric binaural hearing abilities

    SBC: COMPREVAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The practice of evidence-based audiological (re)habilitation requires efficient, easy to use, standardized outcome assessment protocols and instruments with known reliability and validity. Such protocols and instruments are especially important for assessing the speech communication benefits of cochlear implants (CIs) in adults and children. The standard of car ...

    SBIR Phase I 2009 Department of Health and Human Services
  10. Wide Angle X-ray Scattering for Commercial Applications in Drug Lead Discovery

    SBC: SHAMROCK STRUCTURES LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop the use of wide-angle x-ray solution scattering (WAXS) as a routine screening tool for detection of functional interactions between proteins of therapeutic interest and small molecule ligands for the purposes of drug discovery and development. The process of lead discovery presents an early and significant bottleneck in th ...

    SBIR Phase I 2009 Department of Health and Human Services

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