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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Pediatric Acceptable Formulation of Amiodarone
SBC: ACADEMIC PHARMACEUTICALS Topic: N/ADESCRIPTION (provided by applicant): IV amiodarone is the first line therapy for life threatening ventricular as well as supraventricular arrhythmias. However, the Tween 80 and benzyl alcohol diluents limits the rate of administration severely, due to hypotension and myocardial contractile depression. These adverse toxicities contribute to the high mortality of cardiac arrest patients who have ma ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Controlled Release Vascular Grafts
SBC: VesselTek Biomedical LLC Topic: N/ADESCRIPTION (provided by applicant): In the United States, it is estimated that 8 million people suffer from peripheral artery disease (PAD). PAD is characterized by a gradual reduction in blood flow to the muscular arteries of the lower extremities caused by atherosclerosis. For those with severe PAD, lower extremity bypass grafting remains the predominant option for limb salvage. Although native ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Novel Small-molecule TNF-a Modulators as Chemoprotective Agents
SBC: 21ST CENTURY THERAPEUTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): Cisplatin is a widely used cytotoxic agent with therapeutic activity against various tumors, but also with substantial side effects, including nephrotoxicity, hepatotoxicity and myelosuppression. Therefore, a chemoprotective agent which reduces the side effects of cisplatin without affecting it efficacy would have significant clinical benefit. Currently, amifos ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Designed Bioactive Scaffolds for Mandibular Reconstruction
SBC: TISSUE REGENERATION SYSTEMS, INC. Topic: N/ADESCRIPTION (provided by applicant): Craniomaxillafacial (CMF) reconstruction remains a significant challenge due to the complex geometry and the need to restore both esthetics and function, especially for large mandibular segmental defects resulting from tumor resection, trauma or congenital defects. The current clinical gold standard, vascularized free bone flap (VBF), still suffers significant ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Non-invasive Assessment of Insulin Resistance
SBC: BIOCHEMANALYSIS CORPORATION Topic: N/ADESCRIPTION (provided by applicant): The overall objective of this grant is to develop a non-invasive method for assessment of insulin resistance and impaired glucose tolerance (IGT) as a measure of pre-diabetes suitable for application to large-scale screening studies and to individualized preventive strategies in patients at risk for development of diabetes. This new approach is based on the kno ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
MULTIDIRECTIONAL ULTRASONIC BLOOD-FLOW-IMAGING SYSTEM
SBC: BIO-IMAGING RESEARCH, INC. Topic: N/AN/A
SBIR Phase I 1990 Department of Health and Human Services -
MICROHOLOGRAPHIC DIAGNOSIS OF CERVICAL NEOPLASIA
SBC: BIO-LOGIC SYSTEMS CORPORATION Topic: N/ATHIS RESEARCH WILL DEVELOP A MICROHOLOGRAPHIC TECHNIQUE FOR THE DIAGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA (CIN). THE DESIGN OF THE INSTRUMENT WILL ALLOW FOR THE RECORDING OF THE FEMALE GENITAL TRACT, IN PARTICULAR THE CERVIX, WHICH CAN BE SUBSEQUENTLY EXAMINED UNDER A MICROSCOPE WITH RESOLUTION COMPARABLE TO THAT OBTAINED IN PATHOLOGICAL AND HISTOLOGICAL EXAMINATIONS. THE METHOD UTILIZES CON ...
SBIR Phase I 1990 Department of Health and Human Services -
Geostatistical software for the analysis of individual-level epidemiologic data
SBC: BIO-ANALYTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): This SBIR project is developing the first geostatistical software to offer tools that are specifically designed for the geostatistical analysis of both aggregated and individual-level health data, providing: (1) the description of spatial patterns of cancer incidence and mortality rates and identification of nested scales of variation; (2) the spatial interpola ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Case-only Cancer Clustering for Mobile Populations
SBC: BIO-ANALYTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): This project will develop new approaches for evaluating cancer clusters using case-only data. To date three major deficiencies of studies of space-time clustering are that they assume the place-of-residence at time of observation (e.g. diagnosis or death) is representative of place-based exposures over the life course; do not routinely assess the sensitivity of ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
SOLID STATE ENZYME- BASED IMMUNOSENSORS
SBC: Bioquant, Inc. Topic: N/ATHE OBJECTIVE OF THIS SBIR PROJECT IS TO DEVELOP A NEW, SOLID STATE IMMUNOSENSOR WITH CAPABILITIES FOR USE IN HOMES,FARMS, FACTORIES AND OFFICES FOR ON-SITE QUANTITATIVE DETERMINATION OF HORMONES, DRUGS AND TOXINS IN BIOLOGICAL FLUIDS SUCH AS PLASMA, SALIVA, AND URINE. THE PRINCIPLE OF DETECTION WILL BE BASED ON AN ENZYME-AMPLIFIED, IMMUNOELECTROCHEMICAL SOLID STATE DETECTOR THAT CAN BE COUPLED TO ...
SBIR Phase II 1990 Department of Health and Human Services