Award Data

We propose to take our binaural OtoStat-HCP hearing-test system, which was designed for advanced hearing-conservation programs (HCPs), and ruggedize it for use in theater. OtoStat-HCP includes pure-tone audiometry, otoacoustic emission (OAE), and wideband immittance tests. Commercial-off-the-shelf OAE systems are unsuitable for HCPs, so we will: 1) implement next-generation OAE tests to enable qua ...

Vitrification, cryopreserved storage in a “glassy” rather than crystalline phase, is an important enabling approach for tissue banking and regenerative medicine, offering the ability to store and transport cells, tissues and organs for a variety of biomedical uses without the risks of damaging ice formation. Unfortunately, practical application of vitrification has been limited to reproductive ...

Mild Traumatic Brain Injury (mTBI), more commonly known as concussion, is well reported in both civilian and military literature, and has gained significant public attention due to recent conflicts in the Middle East and the extensive media coverage on the dangers of sports related head trauma. The Army has identified the need to develop a simple, easy-to-use, portable screening device to assess m ...

Soldiers displaying symptoms of mild traumatic brain injury (mTBI) need accurate, timely, in-theater assessment of symptoms. Often, initial assessment and diagnosis must be conducted by first-level responders who attempt to assess vestibular symptoms directly following a concussive event; however, these symptoms are often missed, not adequately evaluated, or misdiagnosed due to a lack of familiari ...

Intraocular surgery is usually performed under stereoscopic guidance using a surgical microscope. The surgeon is usually able to see intraocular structures through a clear cornea. However, when the optical clarity of the cornea is severely compromised, visualization of the retina and other intraocular structures is very difficult or impossible. Poor visualization of intraocular structures during s ...

One of the most common military injuries are musculoskeletal injuries (MSI), which inflicts thousands of individuals through combat and occupational risks. These injuries to the upper limb require treatment, assistance, and rehabilitation for the afflicted individual. The proposed Hand Assist/Rehab Orthosis (HARO) is a low-profile, aesthetic, functional system that is able to provide actuation to ...

Hearing loss and tinnitus remain the most common service-connected disabilities, and may be caused by excessive noise exposure, as well as blast and impulse noise.Soldiers who experience tinnitus or mild-to-moderate hearing loss tend to have difficulty understanding speech-in-noise.While peripheral hearing loss can be addressed with amplification through a hearing aid, significant rehabilitation i ...

Hypres is pleased to submit this proposal to continue its Phase II SBIR program and complete the development of a combat-area portable digital MRI (Magnetic Resonance Imaging) system capable of high-resolution Traumatic Brain Injury (TBI) diagnosis in field hospitals. This sequential Phase IIc SBIR program will produce and demonstrate a near production ready state-of-the-art portable MRI system at ...

On-demand cell and tissue samples are critical for both mass trauma care and advanced personalized medical procedures and continue to grow in importance. Biological tissue banks to support these on-demand applications lack safe and effective long-term storage methods. Current cryopreservation techniques and protocols use toxic cryoprotective agents that prevent successful full viability recovery o ...

Progressive noise-induced hearing loss may jeopardize a service members ability to be deployed or continue in communication-critical job duties.It is the fourth leading cause of medical referral for service members returning from deployments.Distortion product otoacoustic emissions (DPOAEs) are a sensitive objective screening tool.However, commercially available DPOAE measurement systems are eithe ...