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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IMMEDIATE FIT USING INNOVATIVE TECHNOLOGY PROSTHETIC SYSTEMS

    SBC: IFIT PROSTHETICS, LLC            Topic: N

    ABSTRACT The principal business interestiFIT Prosthetics LLCwith STTR fundingcreated a new transtibial prosthetic device and demonstrated its safetycomfortand functionIn contrast to conventionally made prosthetic limbsthe iFIT prosthesis is easily fit and aligned on the residual limb in a single sessionDue to its substantial adjustability and customized inner linerthe iFIT device is a comfortable ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Complete genome de novo assembly software for the emerging long read sequencing era

    SBC: DNASTAR, INC.            Topic: 400

    Despite the tremendous success of short read next generation sequencingNGStechnologiestheir inherent inability to establish long range connectivity makes fundamental tasks such as genome closurehaplotype phasing and alternatively spliced transcript characterization all but impossibleNowtwo long read sequencing providersPacific BiosciencesPacBioand Oxford Nanopore TechnologiesONTare producing data ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Continuous Esophageal Pressure Monitoring Catheter with Feeding Tube

    SBC: RUSH RIVER RESEARCH CORP            Topic: NICHD

    PROJECT SUMMARY ABSTRACT Over US adults and children are on mechanical ventilators in intensive care units each year While major advancements in ventilator devices have improved outcomes for critically ill patients current ventilator practice is predominately based on measurements of airway pressure The more relevant pressure particularly to determine if mechanical ventilation is causi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Photoacoustic Quantitative Ultrasound PAQUS device for clinical use

    SBC: IF, LLC            Topic: NIAMS

    Title Development of a Photoacoustic Quantitative Ultrasound PAQUS device for clinical use Abstract The objective of this program is to develop a highly innovative bone assessment device by combining our recently invented photoacoustic physio chemical analysis PAPCA technique with more established quantitative ultrasound QUA techniques After a clinic ready Photoacoustic Quantitative Ultra ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Biological Treatment of Bacterial Keratitis

    SBC: AMEBAGONE INC            Topic: N

    Project Summary Abstract Bacterial keratitisBKis an infection of the cornea thatif left untreatedcan cause blindnessStaphylococcus aureusSaStreptococcus pneumoniaeSpand Pseudomonas aeruginosaPaare three major causes of BK in North AmericaSymptoms of BK include painrednessinflammationand opacity of the affected cornea and loss of visual acuityAmebaGone IncAGpartnered with UW Madison Department of O ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Large-Scale Production of High Purity Human Cortical Glutamatergic Neurons

    SBC: BrainXell, Inc            Topic: 101

    Project Summary AbstractThere exists a dire need for new and more effective drugs to treat disorders of the central nervous systemCNSespecially in mental healthThe pace of approval for new chemical entities is anemicwith an average of just three compounds per year entering the market over the lastyearsUnsurprisinglyclinical trial failure rates for CNS drug development remain greater thanand many m ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Highly sensitive isothermal method and instrument for field diagnostics to facilitate malaria eradication

    SBC: CASCADE BIOSYSTEMS, INC.            Topic: NIAID

    Plasmodium falciparum is the most virulent form of malaria causing million deaths per year Success with patient treatment and a malaria eradication campaign depends significantly on our ability to detect new infections as early as possible in the field rural areas including asymptomatic cases preferably using a small amount of blood e g from a finger prick and to clearly discrim ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Graphene based Nanosensor Device for Rapid Onsite Detection of Dissolved Lead in Tap Water

    SBC: NANOAFFIX SCIENCE LLC            Topic: NIEHS

    PROJECT SUMMARY There is an increasing public concern about monitoring water quality in the entire drinking water supply system especially at the point of use spurred by recent water catastrophes such as the one in Flint Michigan that has caused severe health issues for thousands of children due to the unsafe level of lead in contaminated drinking water Current quantitative detection methods ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Seeing the unseen: Enhancing purification of labile protein complexes and cells with low surface marker expression

    SBC: SALUS DISCOVERY LLC            Topic: 100

    ABSTRACT Asomicsstudies become increasing commonnew methods to identify biomolecule interactions are neededThe ability to isolate specific biomolecules is a fundamental process that spans many biomedical sectors including researchdiagnosticsdrug discoveryand biomarker developmentCommonlysuch isolations are performed by capturing the analyte of interest on a solid structure and then washing away un ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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