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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Consomic rat panels for pharmacogenomic studies and target identification

    SBC: PHYSIOGENIX, INC.            Topic: N/A

    Not avaiable.

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  2. Environmental Assessment Protocol for Special Care Units

    SBC: Innovative Desings And            Topic: N/A

    Research is providing increasing evidence of the potential therapeutic effectsof the physical environment for people with dementia in long-term care settings. Despite this, facilitieshave limited options for learning how to create more supportive environments. Hence few facilities areincorporating those environmental features cited as important in the research literature. Existing optionsare eithe ...

    SBIR Phase II 1996 Department of Health and Human Services
  3. Development of an Antidote for E Coli 0157--H7 Verotoxin

    SBC: OPHIDIAN PHARMACEUTICALS, INC.            Topic: N/A

    E. coli Ol57:H7 is an emerging food-borne pathogen with substantial morbidity and mortality.There are an estimated 20,000 cases of E. coli 0157:H7 infection per year in the United States.However, only 11 states require reporting of the cases to the State Health Department; hence, the actualnumber of cases is likely to be much higher. Twenty-two percent of children acquiring E. coli Ol57:H7infectio ...

    SBIR Phase II 1996 Department of Health and Human Services
  4. Novel Polymorphic Markers for Genetic Analyses

    SBC: PROMEGA CORP.            Topic: N/A

    Our research will identify and develop a new type of polymorphic DNA marker that will allowsimplification and acceleration of genetic analyses. These multiplex-compatible amplifiable markers willhave the advantage of simplified analysis versus current PCR-based marker systems, allowing detectionin a new agarose gel format rather than requiring denaturing polyacrylamide gels. The markers will alsob ...

    SBIR Phase II 1996 Department of Health and Human Services
  5. A new hepatocyte-specific ligand for gene delivery

    SBC: MIRUS BIO CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Given its central role in metabolism and in the secretion of circulating proteins, a large number of genetic or acquired disorders could be corrected by liver-directed gene therapy. However, a safe and effective delivery method for transferring nucleic acids molecules to hepatocytes remains to be perfected. From the Phase I studies, a synthetic peptide that ena ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Enhancing the Vascularization Properties of Skin Tissue

    SBC: Stratatech Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): To date no biological treatment options specifically targeting the hypoxic nature of chronic wounds have been developed and marketed. While administration of individual angiogenic factors may stimulate some aspects of angiogenesis, the simultaneous expression of multiple factors is required to promote morphologically and functionally normal vessels. In this Pha ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Amphiphilic Polycations for Nucleic Acid Delivery

    SBC: MIRUS BIO CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Given its central role in metabolism, the secretion of circulating proteins, and infectious disorders, a large number of genetic or acquired disorders could be corrected by liver-directed delivery of nucleic acids to instill beneficial functions or inhibit deleterious ones. However, a safe and effective delivery method for transferring nucleic acids molecules t ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Arrayed Microfluidic Device for Reconstituted Tissue Assays

    SBC: Bellbrook Labs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There is a strong need in drug discovery for cellular assays that better predict human responses to drugs. A key technical hurdle has been the difficulty of incorporating complex tissue architecture and cellular microenvironments into an assay format that is compatible with the high throughput approaches used for early drug discovery. In this proposal we propos ...

    SBIR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  9. A COMPUTER SYSTEM FOR THE MOLECULAR BIOLOGY LABORATORY

    SBC: DNASTAR, INC.            Topic: N/A

    THE DEVELOPMENT OF RAPID SIMPLE METHODS FOR SEQUENCING DNA HAS LED TO A REQUIREMENT FOR THE DAY TO DAY USE OF COMPUTERSIN THE MOLECULAR BIOLOGY LABORATORY. THE LOW COST OF MICROCOMPUTERS HAS GENERATED CONSIDERABLE INTEREST IN THESE SMALL MACHINES AS THE MOST COST-EFFECTIVE WAY TO MEET THIS REQUIREMENT. THE PURPOSE OF THE FEASIBILITY STUDY PROPOSED HERE IS TO DEFINE THE HARDWARE AND SOFTWARE REQUIR ...

    SBIR Phase II 1984 Department of Health and Human Services
  10. Fatigue Crack Detection Via Differential Thermography

    SBC: Stress Photonics, Inc.            Topic: N/A

    N/A

    SBIR Phase II 1996 Department of Transportation
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