Award Data

DESCRIPTION (provided by applicant): There exists a subculture of gay men at high risk for club drug use and unsafe sexual behavior for whom working out/physique building is central to their life. Currently available prevention material that focuses strictly on drug use or safer sex is not engaging this gay subculture concerned with body image. ACCESS will develop club drug prevention and HIV ri ...

DESCRIPTION (provided by applicant): Physical models of proteins have been proven useful in science classrooms at the high school, undergraduate and graduate levels. These models become discovery tools in the hands of students, turning the abstract concepts of molecular structure and function into something real. Unfortunately, the current method of producing these models, by rapid prototyping in ...

DESCRIPTION (provided by applicant): Drug metabolism problems such as drug-drug interactions and production of toxic metabolites cause almost half of all drug candidate failures during clinical trials. Sulfation is an important type of conjugative drug metabolism that is also used to regulate the level and activity of endogenous hormones. For instance, sulfation regulates the activity of endogenou ...

DESCRIPTION (provided by applicant): Presently, limitations of 3D motion capture systems used in the medical field, sports analysis, and in special effects for movies and video games Include: l) indirect Identification of markers, 2) minimum of 2 video camera requirement to capture any marker, and 3) loss of valuable data due to occlusions and merging. The Doppler properties of radio frequency (RF ...

DESCRIPTION (provided by applicant): The Modified Ashworth scale and manual muscle test are important tools for assessing spasticity and strength. Both lack accuracy and reliability, but given their simplicity, will remain widely used. Their reliability and accuracy could be improved if evaluators could practice against a 'bench mark' standard providing accurate and consistent predefined resistiv ...

DESCRIPTION (provided by applicant): Cystic fibrosis is the most common autosomal recessive genetic disease in the United States. With the recent recommendation for multi-mutation CF screening by the ACMG/ACOG, more labs will be implementing multiplexed genotyping assays. Presently, DNA diagnostic tests for CF are expensive, complicated to run and limited to certain ethnic backgrounds. Using a po ...

DESCRIPTION (provided by applicant): The goal of this project, over Phase I and Phase II, is to develop and validate a new diagnostic platform for biowarfare detection that provides ultrafast design and implementation. Today, both the scientific and security communities believe that advances in biotechnology have increased the concern for misuse in biological weapon programs. As reports of anthra ...

DESCRIPTION (provided by applicant): The goal of this project, over Phase I and Phase II, is to develop and validate a new diagnostic platform for CFTR genotyping that provides closed tube, hands off, inexpensive and rapid testing. The American College of Medical Genetics (ACMG) and American College of Obstetricians and Gynecologists (ACOG) has recently recommended that couples planning to have a ...

DESCRIPTION (provided by applicant): The long-term objective of this project is to develop a new and novel medical monitoring device aimed at benefiting a large class of diabetic individuals. The new device is being called an "Assisted Self- Management Monitor." There are many diseases, such as diabetes, which are considered "self-managed" diseases. With diabetes, it is expected that patients m ...

DESCRIPTION (provided by applicant): The long-term objective of this project is to develop a new and novel medical monitoring device aimed at benefiting a large class of diabetic individuals. The new device is being called an "Assisted Self- Management Monitor." There are many diseases, such as diabetes, which are considered "self-managed" diseases. With diabetes, it is expected that patients m ...