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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Oligonucleotide Enzyme Surrogate (OnES)

    SBC: Accacia International LLC            Topic: CBD08108

    Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Ribozymes for In Vivo Degradation of G-Nerve Agents

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08108

    Given the possibility to administer prophylactic doses of protein bioscavengers inactivating OP nerve agents before they reach their acetylcholinesterase target, much attention has been given to proteins such as human butyrylcholinesterase and paraoxonase I. As small nucleic acid catalysts can exhibit triphosphoesterase activities, the identification of new molecules active against nerve agents w ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. Collective Protection for Military Working Dogs

    SBC: AGAVE BIOSYSTEMS INC.            Topic: CBD08103

    Shelter enclosures for military working dogs in the event of a CB attack is a technology gap identified by the Joint Requirements Office. Important parameters to consider in the design of protective enclosures include low weight and size to minimize transport requirements; rapid setup; and accommodation of canine physiological and psychological comfort needs. The overall operational weight of th ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Low-cost Low-power Wireless Sensor Network Based Highway Incident Detection & Warning System

    SBC: Central Signal LLC            Topic: 07FH4

    More that 52% of the U.S. highway congestion in urban areas is a direct result of highway incidents. Federal and State transportation authorities are searching for quick, low-cost and efficient highway incident detection and warning systems. Several solutions have been proposed but none could meet the requirements of transportation authorities. Central Signal, funded by federal agencies, has done ...

    SBIR Phase I 2008 Department of Transportation
  5. Blood Brain Barrier (BBB) Permeable Encapsulating Agents for Effective Delivery of CNS-active Agents

    SBC: LYNNTECH INC.            Topic: CBD08107

    Drug transport in the central nervous system is highly regulated by the Blood-Brain Barrier (BBB). Most medicines, including many for treating cancer, Alzheimer’s, and stroke, do not meet essential criteria, such as lipophilicity and low molecular weight, required for appreciable transport into the brain. However, endogenous peptides, such as insulin or transferrin, and certain monoclonal anti ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Sequential Isoelectric Point Separation of Proteins Using Non-Gel, Microfluidic System

    SBC: LYNNTECH INC.            Topic: CBD08101

    The measurement of biochemical changes within the human body can provide a means to monitor a person’s physiological health. Many of the biochemicals that provide a snapshot of a person’s health are proteins. The challenge with measuring proteins is the existence of approximately ten orders of magnitude difference in concentration between the most abundant proteins in blood and those typically ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of a Field-Ready Antimicrobial Wound Dressing for the Treatment of Vesicant Burns

    SBC: Stratatech Corporation            Topic: CBD07113

    Cutaneous wounds, such as those resulting from vesicant exposure and thermal injuries, provide an ideal environment for bacterial growth and the complications stemming from wound sepsis. The availability of ready-to-use, antimicrobial skin substitutes that are readily deployed in the field would provide immediate wound closure and reduce the incidence of infection in these wounds. To address thes ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  8. Enhancing the Usability of an Intersection Collision Avoidance Simulation Method

    SBC: Rioux Engineering            Topic: 03FH2

    The TEXAS Model for Intersection Traffic is a high-quality single-intersection microscopic traffic simulation model developed at The University of Texas at Austin. It analyzes in sub microscopic detail the behavior of driver-vehicle units as they go through an intersection and intermix with other traffic flows. It has detailed intersection geometry, path following, microscopic car following, lan ...

    SBIR Phase II 2008 Department of Transportation
  9. Field Energy Recoil Emission Technology (FERET)

    SBC: INVOCON, INC.            Topic: N/A

    Passenger safety concerns have prompted the FAA to elicit energy-sensitive neutron detectors which do not rely on the time-of-flight method and are suitable for use in explosive detection systems. Invocon, Inc. proposes to design an inspection system consisting of an energy source and a detector. Designated FERET sytem, (Field Energy Recoid Emission Technology), it would detect substances identi ...

    SBIR Phase I 1996 Department of Transportation
  10. Advanced Concept Basalt Fiber Reinforcement for Concrete

    SBC: Research & Technology Corp            Topic: N/A

    Extensive research (Ukraine) has shown that high strength continuous fibers of basalt can be produced. These fibers are inexpensive and have exceptionally high strength, stiffness and corrosion resistance. Basalt is a naturally occurring volcanic mineral, consisting a variety concentration of oxides. The product envisioned is a low-cost, corrosion resistant replacement for steel bar in reinforc ...

    SBIR Phase I 1996 Department of Transportation
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