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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Enhancing the Pharmacokinetic Profile of Protein-based Drugs

    SBC: EXTEND BIOSCIENCES INC            Topic: CBD12101

    Many protein-based drugs have limited efficacy due to a short half-life or require intravenous delivery because of low bioavailability when given subcutaneously. Extend Biosciences is developing proprietary carrier molecules that will allow proteins to access a transport pathway for efficient delivery to the vascular space and then maintain a sustained presence in circulation. This would be of par ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  2. An automated, high throughput, resin-free device for large scale protein purification

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12102

    Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  3. Affinity Matrix System for Large-Scale Protein Purification

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: CBD12102

    Though vast improvements have been made in various protein expression platforms, limitations arise in the implementation of current purification methods. Traditional chromatographic methods are time intensive, carry heavy material costs, and are difficult to scale - reducing the benefits achieved in protein expression. Affinity-binding methods are promising for scale-up and swiftness of purificati ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  4. Detection of Liquid Contaminants on Surfaces Using Hyperspectral Imaging

    SBC: EPIR TECHNOLOGIES INC            Topic: CBD12104

    Quick detection of Chemical/Biological (CB) agents in the field can provide critical reconnaissance and contamination avoidance. CB agents pose a serious threat to both civilian and military sectors, and present techniques rely on dangerous collection methods, active measurement through external infrared (IR) sources, and/or are time-consuming. EPIR proposes to provide critically needed improvemen ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  5. Unpressurized High Density Oxygen Storage with Hydrogen Peroxide

    SBC: LYNNTECH INC.            Topic: CBD12105

    Closed circuit breathing apparatus (CCBA, rebreather systems) where exhaled CO2 is removed and con-sumed oxygen replaced, offer much longer working times on a single gas charge than open circuit ones (SCBA). This is achieved through the use of high pressure compressed oxygen. When CCBA units are used in conflict areas this requires the regular delivery of hazardous cargo (high pressure oxygen, 3 ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  6. Regenerable Carbon Dioxide Removal Technology Based on Novel Macroporous Ion Exchange Resins for Closed-Circuit Breathing Apparatus

    SBC: LYNNTECH INC.            Topic: CBD12106

    Currently, the U.S. Military encounters many scenarios where soldiers must enter hazardous areas, yet still maintain isolation from chemical and biological contaminants as well as hazardous materials. This requires the soldiers"respiratory tract be isolated from encountering these contaminants. To accomplish this, the soldiers wear protective suits and/or masks which include a respiratory isolatio ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  7. High Capacity Supported Ionic Liquids for Carbon Dioxide Capture in Rebreather Systems

    SBC: BUSEK CO., INC.            Topic: CBD12106

    Busek Co. Inc. and Ionic Research Technologies, LLC propose to develop a novel carbon dioxide and water removal technology using ionic liquids for closed circuit self-contained breathing apparatus that will extend its operating lifetime, while simultaneously reducing overall weight and logistic burden. Ionic liquids offer unique characteristics including high capacity CO2 capture, tunable gas sel ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  8. Continuous Ionization System for Electrostatic Collection of Bioaerosols in Building Protection Applications

    SBC: MILOW LTD.            Topic: CBD12107

    This proposal presents a method and technology for continuous ionization of bio-aerosols and airborne particles in building protection applications to enable effective removal of the ionized particles from the air flow by an electrostatic collection device. The proposed ionization method is based on a concept of combining a novel method of direct induction charging by an electric field with divers ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  9. A Novel, Aerodynamics-augmented Continuous Ionization System for Electrostatic Collection of Bioaerosols

    SBC: CFD RESEARCH CORPORATION            Topic: CBD12107

    Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
  10. Rapid Sample Transport in Austere Environments

    SBC: NANOHMICS INC            Topic: CBD12108

    Attaining rapid transportation of samples 50-1000 miles in an austere environment requires air transportation. Past applications have included UAV"s which transport the sample to selected location and drop the sample via guided parachute These systems can be quite accurate but they are expensive and relatively large. Balloons are an attractive alternative. They are inexpensive, compact and can be ...

    SBIR Phase I 2013 Department of DefenseOffice for Chemical and Biological Defense
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