Award Data

Protein manufacturing is of paramount importance to chemical and biological defense applications. High-throughput protein purification is a critical need for rapidly scaling the target protein product. Existing purification methods primarly rely on synthetic-resin based chromatography, which is time-consuming, labor-intensive, expensive, and consequently, ill-suited for developing rapid countermea ...

Closed circuit breathing apparatus (CCBA, rebreather systems) where exhaled CO2 is removed and con-sumed oxygen replaced, offer much longer working times on a single gas charge than open circuit ones (SCBA). This is achieved through the use of high pressure compressed oxygen. When CCBA units are used in conflict areas this requires the regular delivery of hazardous cargo (high pressure oxygen, 3 ...

Currently, the U.S. Military encounters many scenarios where soldiers must enter hazardous areas, yet still maintain isolation from chemical and biological contaminants as well as hazardous materials. This requires the soldiers"respiratory tract be isolated from encountering these contaminants. To accomplish this, the soldiers wear protective suits and/or masks which include a respiratory isolatio ...

Safe and efficient air ionization and filtration technology compatible to biodefense applications is of paramount importance. Current ionization methods are energy-intensive, costly, prone to ozone generation, or inefficient, and consequently ill-suited for building protection applications. To overcome these issues, we propose to develop and demonstrate a novel bioaerosol ionization and collection ...

Attaining rapid transportation of samples 50-1000 miles in an austere environment requires air transportation. Past applications have included UAV"s which transport the sample to selected location and drop the sample via guided parachute These systems can be quite accurate but they are expensive and relatively large. Balloons are an attractive alternative. They are inexpensive, compact and can be ...

We propose an innovative Pedestrian Automotive System for Enforcement and Safety (PASES) that combines commercial-off-the-shelf video or camera components and state-of-the-art microwave(radar) systems with sophisticated software that will not only provide more effective enforcement through effective evidentiary information, but will also enable predictive actions based on vehicle and pedestrian be ...

Every asset ages. Pipes, roads, computers, cars, etc. This fact is inevitable. And, as a result of the aging process, every asset suffers a degradation in its intended capability or performance over time. Yet every day, millions of people in the U.S. get up in the morning expecting that they will be able to travel to work, drink clean water, use the Internet, and so on. It usually takes a catastro ...

TRI proposes to develop reliable methodology and protocols for in-service inspection,recertifying and retiring DOT COPVs to maximize service life while ensuring personnel safety. This method must be sufficiently robust to prevent in-service failures, while being straightforward and affordable enough to be conducted at cylinder recertification facilities. To accomplish this with a high degree of co ...

A nondestructive tool will be developed to quatitatively assess residual stress in pipelines from the exterior and through coatings. Residual stress is a critical factor that determines the cracking susceptibility of pipeline steels, but existing methods for measuring mechanical damage in pipeline steels are incapable of quantifying the residual stress levels. A larger gouge or dent does not nec ...

Identification of organophosphates (OPs) based nerve agents, is vital to the protection of U.S. armed forces personnel. Existing detection methods use bulky and expensive laboratory equipment, negating their battlefield use. Colorimetric indicators such as the currently deployed M8 and M9 detection papers are the fastest, cheapest, and easiest type of detector to use; however, these cannot detect ...