Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Carisbamate Treatment for Alcohol Dependence

    SBC: Medication Discovery Texas, Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Though not specifically FDA-approved for this indication, topiramate is among the most effective medication treatments for alcohol dependence. Topiramate is rarely used to treat alcohol dependence, however, because it has prominent side effects including somnolence, dizziness, and cognitive disturbances that require gradual dose titration. Many patients stop ta ...

    STTR Phase II 2013 Department of Health and Human Services
  2. Fluorescence Intensity-based Scoring of Macromolecule Crystallization Plates

    SBC: IXPRESSGENES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Crystallization, followed by subsequent structure determination, is a major step in understanding the structure- function relationship of macromolecules. Understanding macromolecule structure has become a key part in the development of new pharmaceuticals, and is a major area of NIH research. Crystallization however is also the rate limiting step, despite techn ...

    STTR Phase II 2013 Department of Health and Human Services
  3. Alafair Biosciences develops cross-linked polysaccharide hydrogel films to addres

    SBC: ALAFAIR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goal of this STTR project is to develop a pre-formed, naturally-based hydrogel postoperative adhesion barrier with improved handling characteristics, laparoscopic deliverability, and consistent efficacy. Our technology is based on a novel, patented process that imparts exceptional elasticity and toughness on normally brittle, weak materials. Postoperative a ...

    STTR Phase II 2013 Department of Health and Human Services
  4. IYG-Family: Beyond the talk to effective pregnancy, STI, and HIV prevention

    SBC: Radiant Creative Group, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this 3 year Fast-Track STTR is to develop and evaluate a home-based intervention ('it's Your Game- Family') to provide age-appropriate sexual health life skills education and training for children (11-14 years) and to enhance parents' skills and self-confidence in support of this training. IYG-Family (IYG-F) will be an on-line g ...

    STTR Phase II 2013 Department of Health and Human Services
  5. Rapidly boosting innate immunity in the lungs to protect against pneumonia

    SBC: PULMOTECT, INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Pneumonia can be caused by a variety of pathogenic organisms including bacteria, fungi and viruses and is the leading cause of death worldwide. Even in developed countries, pneumonia continues to be the leading cause of death from infection and a serious complication for patients being treated for other diseases. The threat of lung infections is elevated when ...

    SBIR Phase II 2013 Department of Health and Human Services
  6. Clinical Development of a Stable Glucagon Formulation for Bi-hormonal Pump

    SBC: XERIS PHARMACEUTICALS, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The objective of this program is to further the development of a novel, stable, non-aqueous glucagon formulation as an integral component of a bi-hormonal (insulin-glucagon) pump system for treatment of persons with diabetes. The addition of glucagon to the present insulin-based systems will allow greater control of blood glucose with a lower risk of hypoglycem ...

    SBIR Phase II 2013 Department of Health and Human Services
  7. A Hard and Clear, Estrogen-Free Replacement for Bisphenol-A Based Polycarbonates

    SBC: PLASTIPURE, INC            Topic: NIEHS

    DESCRIPTION (provided by applicant): Many peer-reviewed publications show that Bisphenol A (BPA)-based polycarbonate (PC) and all other commonly used hard and clear (HC) plastics (e.g., polyethylene terephthalate (PET), glycol-modified polyethylene terephthalate (PETG), and polystyrene (PS)) leach endocrine disrupting chemicals that most commonly exhibit estrogenic activity (EA). BPA is only one o ...

    SBIR Phase II 2013 Department of Health and Human Services
  8. Field Deployable Vapor Intrusion Monitor

    SBC: Lynntech Inc.            Topic: NIEHS

    DESCRIPTION: Vapor intrusion is the migration of volatile organic chemicals from below ground into overlying buildings and is a major cause of large population exposure to hazardous chemicals. To assess health impacts of exposure to vapor intrusion compounds, monitoring of indoor air is required. Conventional vapor intrusion monitoring is done by on-site sample collection followed by laboratory ...

    SBIR Phase II 2013 Department of Health and Human Services
  9. New Reagents for RNA-based Therapeutic Technologies

    SBC: AM BIOTECHNOLOGIES, LLC            Topic: NIGMS

    DESCRIPTION: New Reagents for RNA-based Therapeutic Technologies Abstract Functional RNA molecules such as aptamers, siRNAs, miRNAs, and related compounds have enormous potential as human therapeutics and as tools for elucidating gene regulation in vivo.To reach this potential, such molecules must be highly potent and highly stable. Unmodified RNAs typically do not come close to meeting these req ...

    SBIR Phase II 2013 Department of Health and Human Services
  10. A New Tool Kit for Whole-Genome Mapping and Complementation in Drosophila

    SBC: Genetivision Corporation            Topic: NIGMS

    DESCRIPTION (provided by applicant): The ultimate goal of this proposal is to generate, maintain, and distribute a new collection of duplication stocks that covers nearly the entire euchromatic autosomal portion of the Drosophila melanogaster genome. Sincethis collection will represent a powerful new set of tools that will benefit virtually all Drosophila geneticists, t is likely that there will b ...

    SBIR Phase II 2013 Department of Health and Human Services
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