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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Phase 1 Clinical Evaluation of NP10679, a GluN2B Selective,Context-Dependent NMDA Receptor Inhibitor for Subarachnoid Hemorrhage

    SBC: NEUROP, INC.            Topic: 102

    Abstract Subarachnoid hemorrhageSAHremains a serious source of neurological morbiditywith approximatelycases reported in the US each yearDespite advances in treating the initial and subsequent bleedspost surgical clipping of the aneurysm is associated with a significant risk of delayed cerebral ischemiaDCIThese events typically occur within the firstdays after aneurysmal rupture and DCI remains th ...

    SBIR Phase II 2017 Department of Health and Human Services
  2. Pre-clinical Development of a Context-Dependent NMADR Neuroprotectant for Treatme

    SBC: NEUROP, INC.            Topic: 102

    DESCRIPTION provided by applicant Cerebral ischemia is a major cause of death and long term disability with high accompanying social and medical costs Approximately Americans suffer a stroke each year at an estimated annual cost of $ B American Heart Association Heart Disease and Stroke Statistics Update Substantial preclinical data support the use of NMDA receptor antago ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Advanced therapeutic for Parkinson's Disease

    SBC: INHIBIKASE THERAPEUTICS            Topic: 105

    Parkinson s DiseasePDis a progressive neurodegenerative disorder that affectsmillion patient in the U Sannually andtomillion people worldwidePD is characterized by disorders of movementwhich are caused by the progressive loss of dopamine neurons in the substantia nigra pars compactaSNpcand autonomic dysfunctionanxietydepressionsleep disorders and cognitive impairment that are due to the degenerati ...

    SBIR Phase II 2017 Department of Health and Human Services
  4. Pre-clinical Development of a Context-Dependent NMADR Neuroprotectant for Treatme

    SBC: NEUROP, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Cerebral ischemia is a major cause of death and long-term disability, with high accompanying social and medical costs. Approximately 795,000 Americans suffer a stroke each year at an estimated annual cost of 73.7B (American Heart Association. Heart Disease and Stroke Statistics, 2010 Update). Substantial preclinical data support the use of NMDA receptor antago ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Economic Spectroscopic Evaluation of Cervical Cancer

    SBC: GUIDED THERAPEUTICS            Topic: N/A

    DESCRIPTION (provided by applicant): Guided Therapeutics has developed the LightTouch(R), a non invasive, point of care device that uses a combination of fluorescence and reflectance spectroscopy to measure the entire ecto-cervix in an imaging format. Our test is intended for use prior to colposcopy by a trained healthcare professional (e.g., physician, nurse practitioner, physician's assistant) t ...

    SBIR Phase II 2009 Department of Health and Human Services
  6. An Automated Platform for High-throughput Network Electrophysiology

    SBC: Axion Biosystems, Inc.            Topic: 102

    DESCRIPTION provided by applicant In response to the program announcement for Phase IIb proposals for complex in vitro brain and behavior tools PA this proposed study automates all aspects of in vitro Microelectrode Array MEA technology to deliver the first ever high throughput MEA based screening system This development will not only enable rapid advancements in the study of basi ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Apical Access System with Universal Connector for Beating Heart LVAD Implantation

    SBC: APK ADVANCED MEDICAL TECHNOLOGIES, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The objective of this proposal is to complete development of a long term universal Apical Access System AAS to improve clinical outcomes and expand the role of left ventricular assist device LVAD therapy The treatment of end stage heart failure HF is the greatest challenge both clinically and economically to the U S health care system today With andg ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Pegasys VR: Integrating Virtual Humans in the Treatment of Child Social Anxiety

    SBC: VIRTUALLY BETTER INC            Topic: NIMH

    DESCRIPTION provided by applicant Anxiety disorders are the most common psychiatric disorders among youth with lifetime prevalence ranging between of the general population Among anxiety disorders social anxiety disorder SAD affects of all youth resulting in significant short and long term impairment including increased likelihood of substance abuse limited academic achievemen ...

    STTR Phase II 2014 Department of Health and Human Services
  9. An Automated Platform for High-throughput Network Electrophysiology

    SBC: Axion Biosystems, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): In response to the program announcement for Phase IIb proposals for complex, in-vitro brain and behavior tools (PA-11-135), this proposed study automates all aspects of in-vitro Microelectrode Array (MEA) technology todeliver the first ever high throughput MEA-based screening system. This development will not only enable rapid advancements in the study of basic ...

    SBIR Phase II 2013 Department of Health and Human Services
  10. Novel WEB Decision Support System for cardiac image interpretation and reporting

    SBC: SYNTERMED INCORPORATED            Topic: NHLBI

    DESCRIPTION (provided by applicant): Today's cardiac imaging field requires diagnosticians to master an ever-expanding knowledge base (KB) while the time to master this knowledge, apply it to specific tasks and reimbursement are steadily shrinking. These constraints pose a serious healthcare problem that inevitably leads to physician's errors. Thus new tools are required to assist physic ...

    STTR Phase II 2012 Department of Health and Human Services

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