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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Ex Vivo Gene Therapy of Hemophilia A

    SBC: EXPRESSION THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Hemophilia A is a bleeding disorder caused by mutations within the factor VIII (fVIII) gene that result in a deficiency of circulating fVIII activity. Current treatment for hemophilia relies on infusion of plasma-derived or recombinant fVIII to restore circulating fVIII activity. This form of therapy is 1) expensive, 2) hard to maintain due to the frequency and ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Automated high-throughput detection anti-HLA antibodies

    SBC: TRANSFUSION AND TRANSPLANTATION TECH            Topic: N/A

    DESCRIPTION (provided by applicant): This is an STTR Phase I application to fund proof of concept studies for a sensitive, accurate, and fully-automated blood screening assay to detect antibodies implicated in TRALI (Transfusion Related Acute Lung Injury). TRALI has become the leading cause of post-transfusion mortality in industrialized countries. Current evidence suggests that many (if not the m ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. In vivo gene detection for cancer analysis

    SBC: VIVONETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a novel dual FRET molecular beacons technology for living cell detection and analysis of cancer. Molecular beacons are dual-labeled oligonucleotide probes with a stem-loop hairpin structure. Hybridization of molecular beacons with target mRNAs corresponding to cancer markers results in fluorescence of the cell. Thus, cancer cells (brig ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
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