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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Semi-Automated Prental Screening Using Maternal Blood

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Scientists have documented the phenomenon of fetal ceils in maternal blood, and envisioned using them for noninvasive prenatal screening. A key limiting factor is the small number of fetal cells in the maternal circulation, making fetal cell isolation difficult and limiting the accuracy of genetic analysis. Current emphasis is on simple, practical and reprod ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Semi-Automated Prental Screening Using Maternal Blood

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Scientists have documented the phenomenon of fetal ceils in maternal blood, and envisioned using them for noninvasive prenatal screening. A key limiting factor is the small number of fetal cells in the maternal circulation, making fetal cell isolation difficult and limiting the accuracy of genetic analysis. Current emphasis is on simple, practical and reprod ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  3. Improved Classifiers for Multiplex FISH

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Automated karyotyping is an important procedure in cytogenetics labs worldwide. Multiplex fluorescence in situ hybridization (M-FISH) is a relatively recent development that uses multicolor chromosome painting probes and multispectral image analysis to identify subtle and complex chromosomal rearrangements. It promises to make automated karyotyping faster, m ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. Improved Classifiers for Multiplex FISH

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Automated karyotyping is an important procedure in cytogenetics labs worldwide. Multiplex fluorescence in situ hybridization (M-FISH) is a relatively recent development that uses multicolor chromosome painting probes and multispectral image analysis to identify subtle and complex chromosomal rearrangements. It promises to make automated karyotyping faster, m ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  5. N/A

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  6. Use of Bioconjugated Quantum Dots in Micro FlowCytometer

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Fluorescent semiconductor nanocrystals or quantum dots have many properties that make them superior to traditional dyes as fluorescent markers. Quantum dots have higher extinction coefficients making them brighter than traditional dyes (up to 1000 times brighter than fluorescein); they do not photobleach; they are not toxic; and different sized quantum dot ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Safety and efficacy of rh-Lactoferrin in Diabetic Ulcers

    SBC: AGENNIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Research Objectives: Determine the safety, pharmacokinetics, pharmacodynamics, and efficacy of topical recombinant human lactoferrin (rhLF) in promoting healing in diabetic ulcers. There are 7.5 million US patients with chronic skin wounds with annual health care costs of $5-9 billion; diabetic ulcers alone cost $4 billion. Current therapies are inadequa ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Expression profiling from microdissected samples

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One objective of the proposal is to develop a product line that will consist of amplified RNA (aRNA) derived from pure populations of cells from various regions of mouse brain. The target cells will be selected by Laser Capture Micro-dissection (LCM). The product line will include aRNA derived from normal mice and from mutant mice that serve as models of hum ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Genomic siRNA Libraries as Tools for Pseudo-Genetics

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed research will enable mammalian cells to be used in mutation/selection experiments to identify genes involved in cellular processes. The objective of the proposal is to develop procedures for preparing siRNA libraries using genomic DNA and cDNA samples as the source material for siRNA templates. Libraries of siRNA vectors could comprise 1,000,000,00 ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Expression profiling from microdissected samples

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One objective of the proposal is to develop a product line that will consist of amplified RNA (aRNA) derived from pure populations of cells from various regions of mouse brain. The target cells will be selected by Laser Capture Micro-dissection (LCM). The product line will include aRNA derived from normal mice and from mutant mice that serve as models of hum ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
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