Award Data

DESCRIPTION (provided by applicant): Mesenchymal stem cells (MSCs) are one of the most extensively studied adult stem cells and have broad potential uses. A few of their uses include, studying developmental pathways, disease modeling, in vitro toxi cology models, compound screening, humanized animal models and potentially cellular therapy. Although MSC are proliferative, a drawback with th ...

DESCRIPTION (provided by applicant): The proposed study utilizes novel electronics and microfabrication techniques to create scalable, in-vitro Multielectrode Array (MEA) technologies. This research will enable rapid advancements in the study of neural int eractions and in the understanding and treatment of neural disorders. Phase I involves two significant developments for neural related research ...

DESCRIPTION (provided by applicant): There is currently a significant demand for proteomics software which enables rapid and accurate data analysis. The advances over recent years in proteomics instrumentation and throughput coupled with the continued expa nsion of biological databases has resulted is researchers being able to produce very large amounts of data in relatively short time periods. Si ...

Not Available

DESCRIPTION (provided by applicant): SiRNAs are synthetic double-stranded oligonucleotides of ~21 base pairs. When applied to cells, siRNAs can effectively and specifically silence their target genes, called RNA interference (RNAi). RNAi has become attract ive tool for functional genomics and a potential class of molecules for human therapeutics. However, almost every siRNA drug company encounters ...

DESCRIPTION (provided by applicant): The hemophilias (A and B) are rare bleeding disorders toward which much scientific and medical effort has been devoted. In 1840, blood transfusion was used for the first time to stop post-operative bleeding in a hemophi lia patient and in 1968 the first commercial coagulation factor concentrate became available. The cloning of the fVIII gene in 1984 facilitated ...

DESCRIPTION (provided by applicant): Development of implantable devices for automated detection, quantification, warning and delivery of therapy to block seizures is a very important unmet medical need. Making such a device as small as possible, minimizin g replacement surgeries, and maximizing device longevity and/or time between battery recharging are some of the most important development driv ...

This Small Business Innovation Research (SBIR) Phase I research project seeks to create the first social community for e-learning, enabling professionals and amateurs to generate, distribute, and share more effective e-learning experiences through collaboration and social interaction. The application is focused on higher education. The community will include students, faculty and alumni engaged in ...

DESCRIPTION (provided by applicant): Inquus proposes to develop a new approach to science education within the framework of a novel e-learning environment that is collaborative, discovery-oriented, user- friendly, and makes use of emerging technologies for new media that are being adopted rapidly across the Web. Specifically, this project will develop biology curricular units within its framework ...

DESCRIPTION (provided by applicant): Mosquitoes are the insect vectors for numerous blood-borne human diseases that cause millions of deaths each year worldwide. Mosquito larvae are filter-feeders that inhabit quiet open-water environments including marshe s, ponds, and eddies along streams and rivers. Depending upon species, the larvae live at various depths in the water column and may be control ...