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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Aerosolized platinum nanoparticle chemotherapy for lung cancer

    SBC: HYLAPHARM LLC            Topic: 102

    Significance Lung cancer is the leading cause of cancer deaths with over new diagnoses annually Survival rate of lung cancer patients is correlated with the extent of lymph node metastasis Standard care includes chemotherapy radiation and or surgery Cisplatin is a first line chemotherapy for lung cancer but systemic intravenous IV delivery is confounded by various toxicities rena ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Preclinical Evaluation of Ancestral Coagulation Factor VIII

    SBC: EXPRESSION THERAPEUTICS, LLC            Topic: NHLBI

    ABSTRACT The development of transformative therapeutics including the possibility of a cure though gene therapy is the sole mission of Expression Therapeutics and continues to be a major research and development activity in the overall $ B USD hemophilia market space However progress in the field has been limited by significant hurdles including the size complexity instability immunogenic ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Media based youth e cig prevention toolkit for community based organizations

    SBC: KDH Research & Communication, Inc.            Topic: NIDA

    KDH Research andamp Communication KDHRC submits this Fast Track SBIR proposal to develop and evaluate AVOID Anti Vaping Online Information Dissemination a media based online toolkit to support community based organizations CBO prevention programming against youth e cigarette e cig use Youth e cig use also known as vaping is a rapidly growing public health threat with use among hi ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Novel sanitizer against viral infections with long lasting effect

    SBC: CAMELLIX, LLC            Topic: NIAID

    Project Summary Abstract Despite mandatory use of hand sanitizer on cruise ships there are reported cruise ship onboard norovirus outbreaks in exceeded the number of norovirus outbreaks outbreaks onboard cruise ships in One of the problems of currently available alcohol based hand sanitizer is that alcohol evaporates in less than seconds after each application to a surface ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Anti CCL mAb to treat castration resistant prostate cancer

    SBC: JYANT Technologies, Inc.            Topic: 102

    Metastatic castration resistant prostate cancer CRPC PCa accounts for of PCa deaths and is associated with skeletal metastases CRPC affects patients differently making this disease difficult for physicians to provide standardized treatments with similar outcomes Docetaxel can prolong the overall survival in patients with metastatic CRPC but current therapies do not provide a cure Doce ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Advanced PML antiviral

    SBC: Inhibikase Therapeutics, Inc.            Topic: NIAID

    Inhibikase Therapeutics is a clinical stagebiopharmaceutical company that has developed a hosttargeted mechanism of action to treat AIDS related and drug induced progressive multifocal leukoencephalopathyPMLPML is a demyelinating disease of the central nervous system and was rarely seen clinically until the era of the HIV epidemic began in the midsDuring the height of the epidemicthe rate of PML o ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Noninvasive Contrast Enhanced Early Detection of Melanoma Liver Metastasis

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: 102

    Abstract The liver is the most common organ for metastasis of various cancersincluding pancreaticovariancolorectalgastric cancers and melanomaUveal melanoma metastasizes inof patients and upon metastasis targets the liver inof these casesThe most common primary malignant liver cancer worldwide is hepatocellular carcinomaHCCThe use of blind liver biopsy as a diagnostic tool for liver cancer has man ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Engineering probiotics to biosynthesize natural substances for microbiome brain research

    SBC: HGG Research LLC            Topic: R

    PROJECT SUMMARY To advance microbiome brain studies the general goals of this collaborative proposal are to provide services to research community by engineering probiotics e g E coli Nissle EcN Bifidobacteria longum Lactobacillus plantarum to biosynthesize various naturally occurring chemicals as prebiotic probiotic conjugates which will be marketed as important laboratory agents ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Large Scale Preparation of Natural Glycans

    SBC: Natglycan, LLC            Topic: 400

    Project Summary Abstract The two major obstacles to progress in glycomics relative to proteomics and genomics are the lack of simple robust and automated methods for determining glycan structures and for synthesis of glycans The net result of this situation is an overall lack of defined glycans for use in functional studies and for use as standards in structural analysis Significant effort has ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Advanced Preclinical Testing of a Novel Recombinant Vaccine Against Zika Virus

    SBC: GEOVAX, INC.            Topic: NIAID

    PROJECT SUMMARY ABSTRACT The recent acceleration in incidence and intensity of human disease caused by Zika virusZIKVinfection has prompted an international outcry for safe and effective countermeasuresCurrently protection against mosquito bites and vector control are the only measures available to prevent ZIKV infectionsA vaccine is urgently neededThe studies proposed here build on previous work ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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