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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A novel peptide-based topical therapeutic to promote corneal regeneration and restore corneal biomechanics following blast and burn injuries

    SBC: FirstString Research, Inc            Topic: A15061

    Ocular traumas resultingfrom explosive or incendiary devices arecommon battlefield injuries. Current therapeutics do not address the biological and molecular processes in corneal wound healing, and therapeuticfailureis associated with corneal ulcers,scarring, and vision loss. Ocular therapeutics that haveregenerative healing properties and restorecorneal biomechanical integrity and can bereadily a ...

    SBIR Phase II 2021 Department of DefenseDefense Health Agency
  2. Platform Agnostic Data Storage Infrastructure

    SBC: MISSION SOLUTIONS GROUP INC            Topic: SOCOM201001

    In this Phase II work program, Mission Solutions Group will develop and deliver to USSOCOM a software prototype system for the Platform Agnostic Data Storage Infrastructure (PADSI) Small Business Innovation Research (SBIR) program. Our technical solution is designed to provide a common framework for multi-model, multi-layer data storage and import/export control as well as advanced Artificial Inte ...

    SBIR Phase II 2020 Department of DefenseSpecial Operations Command
  3. Rational Design of sub-100 nm Polystyrene Particles with a Low Coefficient of Variation in Size

    SBC: TETRAMER TECHNOLOGIES LLC            Topic: NA

    During this Phase II SBIR development program, Tetramer Technologies will develop highlymonodisperse 100-nm and sub-100-nm diameter nanoparticles for use as latex size standards. Highlymonodisperse nanoparticle latexes are needed for improved calibration of electron microscopes, lightscatteringparticle sizing instruments, atomic force microscopes, and particle counters/contamination monitors used ...

    SBIR Phase II 2018 Department of CommerceNational Institute of Standards and Technology
  4. Rational Design of sub-100 nm Polystyrene Particles With a Low Coefficient of Variation in Size

    SBC: TETRAMER TECHNOLOGIES LLC            Topic: NA

    In this Phase I SBIR program, Tetramer Technologies will develop new, commercially attractive, highly monodisperse polystyrene latex standards in a variety of sizes (i.e. 30 nm to 100 nm) via emulsion polymerization processes that employ a surfactant and that are surfactant-free. Surfactant free emulsions will be stabilized through the use of ionic comonomers in the emulsion polymerization. The fo ...

    SBIR Phase I 2017 Department of CommerceNational Institute of Standards and Technology
  5. Optimal Rewarming Solutions for Cryopreserved Tissue Systems: Rapid rewarming reduction of cryoprotectant toxicity and concentration employing magnetic nanoparticles

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15014

    Vitrification, cryopreserved storage in a “glassy” rather than crystalline phase, is an important enabling approach for tissue banking and regenerative medicine, offering the ability to store and transport cells, tissues and organs for a variety of biomedical uses without the risks of damaging ice formation. Unfortunately, practical application of vitrification has been limited to reproductive ...

    SBIR Phase II 2016 Department of DefenseDefense Health Agency
  6. Rapid Rewarming Reduction of Cryoprotectant Toxicity and Concentration Employing Magnetic Nanoparticles

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15014

    We will evaluate a novel warming method, developed by our collaborator John Bischof, that promises solution of one of the remaining barriers for banking of large organs and vascularized composite tissues. The method involves radiofrequency and magnetic nanoparticles to obtain rapid uniform electromagnetic rewarming of biological materials instead of warming from the outer boundary using convection ...

    SBIR Phase I 2015 Department of DefenseDefense Health Agency
  7. Avoiding the Ice Cryolesion in Tissue Cryopreservation with Ice Modulators

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15013

    The long term goal of the proposed research is to develop improved methods for cryopreservation of complex tissues at extreme low temperature. An innovative approach is taken in the proposed line of research, where synthetic ice modulators (SIMs) are combined with established cryoprotective agent (CPA) cocktails to create more favorable conditions for cryopreservation in a process known as vitrifi ...

    SBIR Phase I 2015 Department of DefenseDefense Health Agency
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