Award Data

X-ray fluorescence spectroscopy is a widely used and extremely sensitive analytical technique for qualitative and quantitative chemical analysis. Superconducting Transition Edge Sensor (TES) microcalorimeter detectors have now been developed that achieve an energy resolution of 2 eV for 1.5 keV X-rays, which is sufficient to enable the measurement of the small shift of the X-ray line position that ...

In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

This Small Business Innovation Research (SBIR) Phase II project will perfect a proprietary batch-scale processing technique for fabricating ultrahard and ultrasharp atomic force microscopy (AFM) tips. The new process involves two steps. First, chemical vapor deposition (CVD) is used to coat the tips with a chemically inert, highly conductive, and extremely hard material. Second, a patented process ...

This Small Business Innovation Research (SBIR) Phase II project addresses the analysis needs for monitoring perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in water. PFOA and PFOS are ubiquitous environmental contaminants that have been found at low concentrations in waste water, drinking water, human blood, and in food. Because PFOA, PFOS and other perfluorochemicals are bio ...

This Small Business Innovations Research Phase (SBIR) II project is to support the continued development of using proprietary perfusion decellularization technology to create a fully revascularized cardiac patch for the treatment of ischemic heart disease and congenital heart repair. Current surgical approaches for cardiac reconstruction utilize synthetic materials that do not have the ability to ...

This Small Business Innovation Research (SBIR) Phase I project will demonstrate a new method for monitoring carbon capture and storage (CCS) sites. CCS reduces global warming by using deep geological formations to store large amounts of carbon dioxide formed at power plants or separated from natural gas. The proposed measurement approach combines two recent innovations to create vadose-zone (i.e., ...

This Small Business Innovation Research Program (SBIR) Phase I project will develop improvements to multiphoton microscopy, especially two-photon excitation fluorescence (TPEF). This technology has radically changed the manner in which quantitative biological studies are performed. It is now the tool of choice in dynamic, high-resolution (sub-micrometer) studies because scattering is mitigated, pe ...

This Small Business Innovation Research (SBIR) Phase I project is designed to offer two uniquely tailored thermoresponsive surfaces for the attachment and release of weakly and strongly adherent cells. The commercially available surfaces are highly crosslinked hydrogels that do not work well with either strongly or weakly adherent cells. The goal is to transform the current thermoresponsive cell c ...

This Small Business Innovation Research (SBIR) Phase I project seeks to industrialize a radically new laminar material to demonstrate the value of non-textile but flexible fabric for a variety of different commercial applications. This new material has no fibers and requires no weaving or knitting. Instead, it uses hard and rigid ?elements? - digitally precise shapes of polymers, ceramics or metal ...

This Small Business Innovation Research (SBIR) Phase I project aims to develop a novel chemical sensor technology for inline water quality monitoring. Currently, gas chromatography coupled mass spectroscopy is the most widely used technique for water quality analysis; however, the method is costly, time consuming, and can only be performed by well-trained personnel in a laboratory setting. To meet ...