Award Data

DESCRIPTION provided by applicant Driving while intoxicated DWI is a major public health hazard In the U S there were deaths in caused by alcohol impaired drivers National Highway Traffic Safety Administration NHTSA a The New Mexico Dept of Transportation DoT reported the total DWI cost to New Mexico in alone was over one billion dollars NM DoT In New ...

In the proposed effort, we will leverage this extensive experience and capabilities to realize a frequency agile mmW radiometer that can cover the range of DC-110 GHz and can be scaled to DC-200 GHz under Phase II. Ours is a photonic system that multiplies and up-coverts a low-frequency reference signal onto an optical carrier (laser) using EO modulation, then uses the modulation sidebands to inj ...

DESCRIPTION provided by applicant Analysis of glycoprotein polypeptide sites of carbohydrate attachment and the structures of the glycans present on these proteins requires the combination of high resolution chromatographic separations and sophisticated mass spectrometry Hydrophilic interaction liquid chromatography HILIC has great use in separations of glycopeptides and released glycans exhibitin ...

DESCRIPTION (provided by applicant): The objective of this research project is to develop, evaluate, and disseminate an Internet-based (web) application for SMART Recovery: Overcoming Addictions (OA). OA will be based on the four point cognitive-behavioral program for SMART Recovery (www.smartrecovery.org). The goal of the OA program is to help users learn cognitive and behavioral skills to abstai ...

DESCRIPTION (provided by applicant): Most cellular processes are regulated by reversible protein phosphorylation, which is controlled by protein kinases and phosphatases. Caldera Pharmaceuticals and MedChem Partners propose to develop new probes for characterizing transient protein complexes. MAPK pathways play important roles in cellular differentiation and survival. MAPKs are serine/threonine pr ...

DESCRIPTION (provided by applicant): Caldera Pharmaceuticals will develop quantitative biomarker assays for a set of carcinogens. In Phase I, Caldera will demonstrate the feasibility of using its novel XRpro(R) technology to extract, concentrate, quantify, and characterize carcinogens from biological samples. This will also identify protein adduct biomarkers that are involved in critical carcinoge ...

DESCRIPTION (provided by applicant): Compact Membrane Systems, Inc. proposes to develop novel blood oxygenator membranes with enhanced blood biocompatibility. These will be used to enhance conventional cardio bypass surgery minimizing post operative effects. In addition, they will provide a key element for long term blood oxygenation associated with extracorporeal membrane oxygenation, acute respi ...

DESCRIPTION (provided by applicant): Hydrogen sulfide (H2S), once identified exclusively as a pernicious toxic gas, is now recognized as a key participant in a myriad of physiological functions. Activity occurs in a wide variety of systems including periodontal, cardiovascular, neurological, inflammatory, and gastrointestinal. We have selected one of these areas and propose new research for examin ...

DESCRIPTION (provided by applicant): Radiation therapy is one of the primary weapons in the battle against cancer, but even with the advances we have made, there remains significant room for improvement in radiation-based treatment technologies. Proton therapy is now considered the most advanced form of radiation therapy available for cancer treatment, but the size and cost of currently available ...

DESCRIPTION (provided by applicant): The purpose of this Phase I grant is to establish the feasibility of effecting a measurable positive change in compliance among diabetics with regards to necessary follow-up screening exams and ophthalmic care through a purpose-made, culturally competent, printed medium traditionally used for entertainment: the fotonovela. We will demonstrate statistically the ...